Position Statement: Nonanesthesiologist Administration of Propofol for GI Endoscopy (original) (raw)

Quality of sedation with propofol administered by non-anesthetists in a digestive endoscopy unit: the results of a one year experience

Revista EspaƱola de Enfermedades Digestivas, 2018

Introduction: research has shown that an endoscopist-nurse clinical team can perform sedation with propofol effectively, safely and efficiently. To do so, it is essential to provide specific and appropriate training in the necessary skills. The main aim of the present study was to evaluate the quality of the sedation procedure administered by non-anesthetists in a digestive endoscopy unit, one year after its introduction. Methods: a prospective cohort study was performed in patients given propofol sedation by non-anesthetists. Subsequently, a random sample of clinical records was selected in order to evaluate the adherence of professionals to the quality criteria and to assess the rate of adverse events related to sedation. Results: a total of 595 procedures were performed under propofol sedation during the study period. The rate of adverse events was 2.4% (n = 507), mainly involving hypotension and hypoxemia. Adherence to the sedation procedure was above 80% for most of the applicable criteria, although it was lower for the completion of ASA risk evaluation. 2 Conclusions: the results of the study suggest that propofol can be administered safely and effectively by a qualified endoscopist-nurse team, in patients with an ASA I-II risk. Audits of adherence by medical staff to the recommended procedure facilitate the identification of areas for improvement; further work is needed on the aspects that have not yet been consolidated.

Efficacy and safety of propofol sedation during urgent upper gastrointestinal endoscopy--a prospective study

Collegium antropologicum, 2003

The aim of this study was to investigate both the efficacy and safety of sedation with propofol during urgent therapeutic gastroscopy in patients with upper gastrointestinal bleeding. This prospective study included a total of 110 patients. Propofol was administered intravenously at the starting dose of 1 mg/kg body weight and was followed by repeated doses. Oxygen saturation and heart rate were monitored by pulse oxymetry. The mean dose of propofol administered was 161 +/- 49 mg. Urgent upper GI endoscopy under propofol sedation was successful in 98% of cases. Endoscopists rated the sedation as good in 83.6%, satisfactory in 14.5%, and poor in 1.8% of patients. Potentially harmful drop in oxygen saturation below 85% was observed in 5.5% of patients, whereas a temporary drop in heart rate below 50 beats/min was observed in 11.8%, not requiring any intervention. Almost 93% of patients could not remember the beginning or the end of the intervention. This data demonstrates that sedatio...

Propofol administration by endoscopists versus anesthesiologists in gastrointestinal endoscopy: a systematic review and meta-analysis of patient safety outcomes

Canadian journal of surgery. Journal canadien de chirurgie, 2018

With a growing demand for endoscopic services, the role of anesthesiologists in endoscopy units must be reassessed. The aim of this study was to compare patient outcomes in non-anesthesiologist-administered propofol (NAAP) versus anesthesiologist-administered propofol (AAP) during routine endoscopy. We systematically searched Medline, CINAHL, Embase, Web of Science, CENTRAL and the grey literature for studies comparing NAAP and AAP. Primary outcomes included endoscopy- and sedation-related complications. Secondary outcomes included measures of endoscopy quality and of patient and endoscopist satisfaction. We reported treatment effects using random-effects models. Of 602 articles identified, 5 met the inclusion criteria. Most studies included only patients with an American Society of Anesthesiologists (ASA) classification of I or II. Non-anesthesiologist-administered propofol did not result in increased rates of airway intervention (odds ratio [OR] 1.07, 95% confidence interval [CI] ...

Endoscopist controlled administration of propofol: an effective and safe method of sedation in endoscopic procedures

Revista Espanola De Enfermedades Digestivas, 2006

Objectives: propofol is a short-acting, hypnotic agent that is increasingly being used for gastrointestinal endoscopic sedation. There are concerns about the use of propofol by non anesthesiologists due to its potential for respiratory and cardiovascular depression. This report describes our experience concerning effectiveness and safety of propofol administered in endoscopic procedures by the endoscopist and the assistant nurse.

Propofol Sedation in Diagnostic Upper Gastrointestinal Endoscopy

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 2020

Background: Sedation are commonly used these days in patients that having gastrointestinal endoscopy. Propofol is sedative agent that commonly used in endoscopy procedure. Method: All patients who were performed diagnostic EGD in Abdi Waluyo Hospital's Gastrointestinal Endoscopy Unit from January 1st 2017-31st December 2017, included in this study. The amount of Propofol, duration during hypnosis/sedation and adverse effects were all recorded. Results: 170 patients were performed diagnostic EGD with Propofol sedation, most of them were male (87 patients, 51,5%). The median age was 48,78 + 14. The median Body Mass Index (BMI) was 24.45. The median of duration of hynosis (sedation) during EGD was 5 minutes. The median of propofol total dose during EGD was 180 mg. Adverse effects that found during Propofol sedation are muscle twitching(10.6% patients) and pain in area of injection(80% patients). Conclusion: The duration of propofol hypnosis/sedation during Esophagogastroduodenoscopy examination was 5 minutes. Propofol total dose needed for diagnostic EGD was 180 mg. The common adverse effects of propofol are muscle twitching and pain in area of injection.

Safety analysis of endoscopist-directed propofol sedation: A prospective, national multicenter study of 24 441 patients in German outpatient practices

Journal of Gastroenterology and Hepatology, 2014

Background and Aim: Since 2008, there exists a German S3-guideline allowing nonanesthesiological administration of propofol for gastrointestinal endoscopy. In this prospective, national, multicenter study, we evaluated the safety of endoscopist-administered propofol sedation (EDP) in German outpatient practices of Gastroenterology. Methods: In this multicenter survey of 53 ambulatory practices of Gastroenterology, we prospectively evaluated 24 441 patients that had received EDP. We recorded adverse events during the endoscopic procedure and additionally retrieved questionnaires investigating subjective parameters 24 h after the endoscopic procedure. Results: In 24 441 patients 13 793 colonoscopies, 6467 esophagogastroduodenoscopies, and 4181 double examinations were performed. In this study, 52.1% of the patients received propofol mono-sedation, and 47.9% received a combination of midazolam and propofol. Major adverse events occurred in four patients (0.016%) enrolled to this study (three mask ventilations and one laryngospasm). Minor adverse events were observed in 112 patients (0.46%) with hypoxemia being the most common minor event. All patients with adverse events recovered without persistent impairment. Minor adverse events occurred more frequently in patients sedated with propofol mono compared to propofol and midazolam (P < 0.0001) and correlated with increasing propofol dosages (P < 0.001; Pearson correlation coefficient r = 0.044). Twenty-four hours after the endoscopy, patients sedated with propofol plus midazolam stated a significantly reduced sensation of pain (P < 0.01) and improved symptoms of dizziness, nausea and vomiting (P < 0.001) compared to patients having received propofol mono-sedation. Conclusion: Four years after the implementation of a German S3-Guideline for endoscopic sedation, we demonstrated that EDP is a safe procedure.