Management of Renal Replacement Therapy in Acute Kidney Injury: A Survey of Practitioner Prescribing Practices (original) (raw)
2007, Clinical Journal of the American Society of Nephrology
Data on current practices for management of renal replacement therapy in acute kidney injury (AKI) are limited, particularly with regard to the dosing of therapy. We conducted a survey of practitioners at the 27 study sites participating in the VA/NIH Acute Renal Trial Network (ATN) Study prior to initiation of subject enrollment to ascertain the local prevailing practices for management of renal replacement therapy in critically ill patients with AKI. Surveys were returned from 130 practitioners at 26 of 27 study sites; the remaining study site provided aggregate data. Intermittent hemodialysis and CRRT were the most commonly utilized modalities of renal replacement therapy, with SLED and other "hybrid" treatments used in fewer than 10% of patients. Intermittent hemodialysis was most commonly provided on a thrice weekly or every-other day schedule, with only infrequent assessment of the delivered dose of therapy. Most practitioners reported that they did not dose CRRT based on patient weight. The average prescribed dose of therapy corresponded to a weight-based dose of no more than 20 to 25 mL/kg/hr. These results provide insight into clinical management of renal replacement therapy and provide normative data for evaluation of the design of ongoing clinical trials.
Sign up for access to the world's latest research.
checkGet notified about relevant papers
checkSave papers to use in your research
checkJoin the discussion with peers
checkTrack your impact
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.