Optics of living tissues with controlled scattering properties (original) (raw)
Proceedings of SPIE - The International Society for Optical Engineering
Results of in vitro and in vivo experimental studies of the optical properties of the rabbit eye, the human eye sclera, and the human skin controlled by administration of osmotically active chemicals, such as glucose, trazograph, and the 50% -Glycerol + DMSO solution are presented. Glucose and other solutions administration induces the diffusion of matter and as a result the equalization of the refractive indices of collagen fibrils and ground material, and corresponding changes of reflectance and transmittance spectra of living tissue. Transmittance and reflectance spectra measurements of tissues, as well as optical anisotropy determination using color measurements were provided. The diffusion coefficient for glucose within scleral tissue was estimated; the average value is 6 6 10 64 . 1 10 62 . 5 − − ⋅ ± ⋅
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