Effect of cyclosporin A on the uptake of D3-selective PET radiotracers in rat brain (original) (raw)
PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS
Aren van Waarde
2004
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Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate 11C-Metoclopramide Assessed with PET Imaging in Humans
W. Jager
Journal of Nuclear Medicine, 2019
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{"__content__"=>"P-glycoprotein (ABCB1) inhibits the influx and increases the efflux of C-metoclopramide across the blood-brain barrier: a PET study on non-human primates.", "sup"=>{"__content__"=>"11"}}
Irène Buvat
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018
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N-desmethyl-Loperamide Is Selective for P-Glycoprotein among Three ATP-Binding Cassette Transporters at the Blood-Brain Barrier
Kyle Innis
Drug Metabolism and Disposition, 2010
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In Vivo Evaluation of P-Glycoprotein Modulation of 8 PET Radioligands Used Clinically
Kazuhiko Yanai
2000
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Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
Obaidur Rahman
Drug Metabolism and Disposition, 2009
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Evaluation of Drug Penetration into the Brain: A Double Study by in Vivo Imaging with Positron Emission Tomography and Using an in Vitro Model of the Human Blood-Brain Barrier
Bertrand Tavitian
Journal of Pharmacology and Experimental Therapeutics, 2005
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Blocking of efflux transporters in rats improves translational validation of brain radioligands
Nakul Raval
EJNMMI Research
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Transport across the blood-brain barrier: stereoselectivity and PET-tracers
Adriaan A Lammertsma
Molecular Imaging and Biology - MOL IMAGING BIOL, 2004
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In Vitro and In Vivo Characterization of Two C-11-Labeled PET Tracers for Vesicular Acetylcholine Transporter
Joshua Parsons
Molecular Imaging and Biology, 2014
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Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs
Kevin Read
Journal of Cerebral Blood Flow & Metabolism, 2012
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11C-Loperamide and Its N-Desmethyl Radiometabolite Are Avid Substrates for Brain Permeability-Glycoprotein Efflux
Jong-In Hong
2008
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Effect of a P-glycoprotein inhibitor, cyclosporin A, on the disposition in rodent brain and blood of the 5-HT1A receptor radioligand, 11C-(––)-RWAY
Jong-In Hong
Synapse, 2007
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Increased permeability-glycoprotein inhibition at the human blood-brain barrier can be safely achieved by performing PET during peak plasma concentrations of tariquidar
Ritwik Bhatia
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015
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Imaging the impact of the P-glycoprotein (ABCB1) function on the brain kinetics of metoclopramide
Irène Buvat
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015
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P-Glycoprotein Function at the Blood-Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide
Bart Van Berckel
Journal of Nuclear Medicine, 2010
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P-Glycoprotein Function at the Blood-Brain Barrier Imaged Using 11C-N-Desmethyl-Loperamide in Monkeys
Jeih-san Liow
Journal of Nuclear Medicine, 2008
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Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: a PET Imaging Study
Peng Hsiao
Drug metabolism and disposition: the biological fate of chemicals, 2015
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Characterization of [11C]RO5013853, a novel PET tracer for the glycine transporter type 1 (GlyT1) in humans
Vanessa Raymont, A. Kumar
2013
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PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain
Magnus Schou
Synapse, 2004
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Human Brain Imaging and Radiation Dosimetry of 11C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein
Jeih-san Liow
Journal of Nuclear Medicine, 2009
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Imaging P-glycoprotein transport activity at the human blood-brain barrier with positron emission tomography
Mark Muzi
Clinical Pharmacology & Therapeutics, 2005
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