Verrucous carcinoma of the tibia arising after chronic osteomyelitis: a case report (original) (raw)
Osteomyelitis: A Literature Review
JURNAL BIOMEDIK (JBM)
Abstrak: Infeksi pada tulang dan sendi masih merupakan kasus yang menantang. Kondisi ini memberikan banyak penyulit baik kepada dokter maupun pasien. Meski terapi antibiotika dilaporkan memberikan hasil yang memuaskan pada banyak kasus infeksi, tidak demikian pada kasus infeksi tulang dan sendi. Hal ini berhubungan dengan struktur anatomi dan fisiologi dari tulang. Diperlukan sebuah strategi tata laksana yang baik untuk mencapai hasil yang optimal. Prinsip dasar yang utama dalam mencapai pengobatan yang optimal ialah penegakan diagnosis awal yang tepat, termasuk di dalamnya proses investigasi pemeriksaan mikrobiologi dan patologi. Diperlukan pengertian dasar serta pengenalan kembali anatomi, fisiologi, patofisiologi, dan tata laksana terkini tentang osteomielitis untuk mencapai tatalaksana yang optimal.Kata kunci: diagnosis dan tata laksana osteomielitis: Infection in bone and joint is still a challenging case. It gives a lot of problems and frustration to the physician and patient....
Garré’s sclerosing osteomyelitis: case report
Revista Brasileira de Ortopedia (English Edition), 2014
The aim of this study was to report on a rare case of Garré's sclerosing osteomyelitis. The patient was a 54-year-old woman with a history of treatment for lupus using corticoids for 20 years, and for osteoporosis using alendronate for five years. She presented edema and developed a limitation of left knee movement one year earlier, with mild effusion and pain on metaphyseal palpation, but without fever. She was in a good general state, without local secretion. Images of her knee showed trabecular osteolysis of the distal metaphysis of the femur and a periosteal reaction in both proximal tibias and both distal femurs, compatible with chronic osteomyelitis of low virulence and slow progression. Magnetic resonance imaging showed T2 hypersignal in the femur and tibia. Curettage was performed on the left distal femur, with release of secretion, but this was negative on culturing. A biopsy showed chronic infection and inflammation, fibrosis, xanthogranulomatous reaction and foci of suppuration. Antibiotic therapy was administered for six months. The etiology was not clarified: bacterial infection was suspected, but culturing was generally negative. The chronic process was maintained by low-virulence infection or even after treatment. The differential diagnoses were fibrous dysplasia, syphilis, pustulosis palmoplantaris, rectocolitis, Crohn's disease, SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) and Paget's disease. The unifocal diseases were osteoid osteoma, Ewing's disease, osteosarcoma and eosinophilic granuloma.
An Unusual Case Report of Two Bone Osteomyelitis With Long-Term Follow-up
The Foot and Ankle Online Journal, 2008
A 49 year-old patient, with a history of rheumatoid arthritis, presents with suspected septic arthritis of the ankle and subtalar joints. The patient was found to have osteomyelitis of both the talus and calcaneus. The patient was treated by debridement, antibiotic impregnated PMMA beads, and ultimately, a subtalar joint fusion. This case illustrates the importance of the early recognition and diagnosis, the possible sequelae, and the need for aggressive treatment of a septic joint.
OSTEOMYELITIS: FROM DIAGNOSIS TO TREATMENT (Atena Editora)
OSTEOMYELITIS: FROM DIAGNOSIS TO TREATMENT (Atena Editora), 2023
This study aimed to carry out a bibliographic review about Osteomyelitis, a bone inflammation caused by an infection. Since 1984, osteomyelitis has been known, which is a bone inflammation due to a constant infection process, which occurs when a pathogen has access to the bone through an exposed wound, or resulting from trauma or a post-surgical procedure. To make the diagnosis, when the individual presents signs and symptoms (fever, chills, abscesses, edema and local erythema), which can be localized or systemic. We identified it through alterations in an X-ray exam, also requiring complementary exams. This pathology has different classifications, but with a standard initial treatment, with the use of drugs and even surgical intervention in more severe cases. The highlight is given to the group most affected by the pathology, men, whites aged over 60 years are the most seriously affected. This way, it is necessary to give due importance to carrying out more research and forms of prevention for this pathology and its consequences.
A case discussion on osteomyelitis: A Case Report
National Journal of Research in Ayurved Science, 2018
Leeches found very effective and 100% curative role in various non curable diseases by other pathies. Jaloka is a treasure and blessing of Ayurveda never says no to any problem that’s why it is accepted worldwide for various disorders. Acharya Sushruta and Vagbhata advised various diseases for Jalokavcharan. Ashtishotha (Ostetomylitis) is one of them considering this, we tried on the case of osteomylitis and we got miracle result.
Chronic Osteomyelitis of the Navicular Bone: Case Report and Review of Literature
SAS Journal of Surgery
Osteomyelitis of the navicular bone is not common; the few reported cases are haematogenous osteomyelitis of the navicular bone and were mostly seen in children and another case seen in an adult. We are presenting a case of domestic accident resulting in chronic osteomyelitis of the navicular bone in an adult caused by direct inoculation of infection following traditional bone setter’s mismanagement and subsequent surgery on the same foot. Consent is duly obtained from the patient to present this case report. The aim of this case presentation is to highlight the need for high index of suspicion of osteomyelitis of the bones of the foot in adult which are not necessarily secondary to haematogenous spread as seen in children but due to direct inoculation of micro- organisms, the study also seeks to demonstrate a complete cure of chronic osteomyelitis following proper debridement of the sequestrum with adequate use of the relevant antibiotics for the specified durations of administrati...
Osteomyelitis in adults: A prospective study of 60 cases
International Journal of Orthopaedics Sciences, 2018
Introduction: The exact definition of osteomyelitis is inflammation of bone or bone marrow or both, but for all practical purposes this inflammation invariably is the result of infection. Various factors responsible for osteomyelitis include vascular insufficiency due to any cause, hematogenous spread of infection from a distant focus and surgery or trauma. Acute Osteomyelitis usually presents with fever, chills, pain or irritability. The classic signs of inflammation, including swelling, or redness and limited joint movement may also occur. Chronic osteomyelitis may present with bone destruction and sequestrum formation and is a difficult form of osteomyelitis to treat. Aims and Objectives: To study demographic details, organisms involved and outcome of treatment in patients with osteomyelitis. Materials and Methods: After obtaining approval from institutional ethical committee we conducted a prospective study of 60 patients diagnosed with either acute, subacute or chronic osteomyelitis on the basis of imaging and culture and sensitivity. Patients were included in this study on the basis of predefined inclusion criteria and were treated by antibiotics and when necessary surgical intervention was done. In cases of skeletal tuberculosis appropriate antikochs treatment was given. Outcome of treatment was studied over a follow up period of 1 year. The data was tabulated and analyzed using SPSS 16.0 version software. Results: Out of 60 cases of either acute, subacute or chronic osteomyelitis there were 38 males (63.33%) and 22 females (36.66%) with a M:F ratio of 1:0.57. Most common age group affected was found to be between 51-60 (36.66%) years. Acute, subacute and chronic osteomyelitis was seen in 71.66%, 11.66% and 16.66% patients respectively. Most common bones involved were Tibia (20%) and Femur (18.33%) followed by iliac bones (15%) fibula (11.66%) and vertebrae (11.66%). In most of the cases (36/60) contagious spread or trauma was the mechanism of infection. Comorbidities like hypertension, diabetes, chemotherapeutic agents or steroid intake and immunosuppression was present in 32 (53.33%) patients. S. Aureus (25/60) followed by Pseudomonas (7/60) and enterococci (7/60) were commonly isolated organisms. Atypical mycobacterial infection was seen in 1 patient who was immunocompromised. 40 patients were completely cured while remaining 10 patients had some or the other problem associated with chronic osteomyelitis. Amputations was done in 4 cases and septic arthritis developed in other 2 cases. 4 patients died during study period due to causes unrelated to osteomyelitis. Conclusion: Diagnosis as well as management of osteomyelitis is a challenge for treating orthopaedician. Knowledge of predisposing factors, presenting complaints, possible complications and proper management is essential for successful management of acute as well as chronic osteomyelitis.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2019
An 11-year-old male child from a village in Indo-Bangladesh border, son of a manual labourer and holding a BPL (Below Poverty Line) card, presented to the orthopaedic outpatient department with a discharging sinus along with an exposed piece of bone over the lower lateral aspect of his right leg since seven months. The patient was apparently well prior to that, when he first developed an itching and burning sensation at the same site of his right leg followed by an insidious onset of swelling around that region with redness and high grade fever. He was first treated by a traditional healer who applied some herbal preparation over the swelling, following which he developed a discharging sinus leading to an exposed bone with a non-healing wound. He was subsequently taken to a general practitioner, who prescribed some medications as well as daily dressing of the wound. With the condition of the wound worsening and the child's overall health deteriorating, he was eventually referred to our centre for further management.
Chronic osteomyelitis on an old compound fracture
Journal of College of Medical Sciences-Nepal, 2012
Osteomyelitis is a common complication of compound fracture of long bones which is difficult to treat. We present a similar case of chronic osteomyelitis on an old malunited compound fracture of distal third left femur in a nine years old child. Management of such cases requires surgery with immobilization, long term appropriate antibiotics and intensive follow up. Journal of College of Medical Sciences-Nepal,2012,Vol-8,No-2, 54-57 DOI: http://dx.doi.org/10.3126/jcmsn.v8i2.6840