Deformylase as a novel antibacterial target (original) (raw)

Peptide Deformylase as an Antibacterial Drug Target: Assays for Detection of Its Inhibition in Escherichia coli Cell Homogenates and Intact Cells

Christian Hubschwerlen

Antimicrobial Agents and Chemotherapy, 2001

View PDFchevron_right

Peptide Deformylase As An Antibacterial Drug Target: Target Validation and Resistance Development

christian hubschwerlen

Antimicrobial agents …, 2001

View PDFchevron_right

Peptide deformylase: a target for novel antibiotics?

Dehua Pei

Emerging Therapeutic Targets, 2001

View PDFchevron_right

Characterization of a Human Peptide Deformylase: Implications for Antibacterial Drug Design †

Kiet Nguyen

Biochemistry, 2003

View PDFchevron_right

Structural Basis for the Design of Antibiotics Targeting Peptide Deformylase

Dehua Pei

Biochemistry, 1999

View PDFchevron_right

Peptide Deformylase: A New Target in Antibacterial, Antimalarial and Anticancer Drug Discovery

firoz khan

View PDFchevron_right

Determination of Substrate Specificity for Peptide Deformylase through the Screening of a Combinatorial Peptide Library †

Yun-Jin Hu

Biochemistry, 1999

View PDFchevron_right

In Silico Study of the Selective Inhibition of Bacterial Peptide Deformylases by Several Drugs

Abderrahmane Bensegueni

Journal of Proteomics & Bioinformatics, 2010

View PDFchevron_right

Characterization of peptide deformylase homologues from Staphylococcus epidermidis

F. Gotz

Microbiology, 2010

View PDFchevron_right

The evolution of peptide deformylase as a target: Contribution of biochemistry, genetics and genomics

Rustini Ruslan

Biochemical Pharmacology, 2006

View PDFchevron_right

Ligand-Induced Changes in the Structure and Dynamics of Escherichia coli Peptide Deformylase

carlos amero

Biochemistry, 2009

View PDFchevron_right

In silico development of broad spectrum antibacterial by targeting peptide deformylase

Asif Khursheed

2013

View PDFchevron_right

New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

Thierry Meinnel

The Journal of antimicrobial chemotherapy, 2012

View PDFchevron_right

Theoretical study of Escherichia coli peptide deformylase inhibition by several drugs

abdelouahab chikhi

In Silico Biology, 2006

View PDFchevron_right

Peptide Aldehyde Inhibitors of Bacterial Peptide Deformylases

Stephan Grant

Archives of Biochemistry and Biophysics, 1999

View PDFchevron_right

Antibiotic Activity and Characterization of BB3497, a Novel Peptide Deformylase Inhibitor

ANDANI LEONAH

Antimicrobial Agents and Chemotherapy, 2001

View PDFchevron_right

Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents

Xinyi Ngew

Antimicrobial Agents and Chemotherapy, 2006

View PDFchevron_right

Crystal Structure of Type II Peptide Deformylase from Staphylococcus aureus

Eric Baldwin

Journal of Biological Chemistry, 2002

View PDFchevron_right

Peptide Deformylase in Staphylococcus aureus: Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene

Joaquim Trias

Antimicrobial Agents and Chemotherapy, 2000

View PDFchevron_right

A unique peptide deformylase platform to rationally design and challenge novel active compounds

Thierry Meinnel

Scientific Reports, 2016

View PDFchevron_right

Identification of a Potent Peptide Deformylase Inhibitor from a Rationally Designed Combinatorial Library

Dehua Pei

Journal of Combinatorial Chemistry, 2000

View PDFchevron_right

Crystal Structure of the Escherichia coli Peptide Deformylase

Dehua Pei

Biochemistry, 1997

View PDFchevron_right

Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion 1 1Edited by F. E. Cohen

Stephane Villoing

Journal of Molecular Biology, 1997

View PDFchevron_right

Virtual Screening Approach of Bacterial Peptide Deformylase Inhibitors Results in New Antibiotics

Hanane Boucherit, Sezer Okay

Molecular informatics, 2017

View PDFchevron_right

The Crystal Structures of Four Peptide Deformylases Bound to the Antibiotic Actinonin Reveal Two Distinct Types: A Platform for the Structure-based Design of Antibacterial Agents

Magali Mathieu

Journal of Molecular Biology, 2002

View PDFchevron_right

The carboxy-terminal end of the peptide deformylase from Mycobacterium tuberculosis is indispensable for its enzymatic activity

Pradip Chakraborti

Biochemical and Biophysical Research Communications, 2005

View PDFchevron_right

Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion

Thierry Meinnel

Journal of Molecular Biology, 1997

View PDFchevron_right

Substrate recognition and selectivity of peptide deformylase. similarities and differences with metzincins and thermolysin

Thierry Meinnel

Journal of Molecular Biology, 1999

View PDFchevron_right