Methods for Detection of Protein–Proteinnl and Protein–DNA Interactions Using HaloTag ™ (original) (raw)

2008, Affinity Chromatography

AI-generated Abstract

This edition of Methods in Molecular Biology focuses on advanced affinity chromatography techniques, emphasizing new protocols for protein purification and their applications in high-throughput screening. It covers methods for protein tagging, ligand selection, and diverse applications ranging from DNA purification to the isolation of phosphorylated proteins. The integration of phage display technology for selecting peptide ligands further enriches the discussions on effective affinity chromatography methods.

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Thirty years of affinity chromatography

Reactive and Functional Polymers, 1999

Affinity chromatography was introduced 30 years ago and is the most powerful tool for purification of biologically active molecules. Affinity chromatography has also had a major impact and virtually revolutionized the entire field of modern biology, molecular biology, biochemistry, medicine and biotechnology. The development of affinity chromatography has led to many other studies and applications in which the concept of molecular recognition and biorecognition is used.

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