Crystal Structures of a Schistosomal Drug and Vaccine Target: Glutathione S-Transferase fromSchistosoma japonicaand its Complex with the Leading Antischistomal Drug Praziquantel (original) (raw)

1995, Journal of Molecular Biology

The Scripps Research parasitic helminths, is a major vaccine target and an attractive drug target Institute, Department of against schistosomiasis and other helminthic diseases. Crystal structures of Molecular Biology-MB4 the 26 kDa GST from the helminth Schistosoma japonica (SjGST) have been 10666 North Torrey Pines Road, La Jolla, CA 92037 determined for the unligated enzyme (resolution = 2.4 Å, R-factor = 19.7%) U.S.A.

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Crystal Structures of a Schistosomal Drug and Vaccine Target: Glutathione S-Transferase fromSchistosoma japonicaand its Complex with the Leading Antischistomal Drug Praziquantel (original) (raw)

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