HLA antigens in depression and hypersomnia (original) (raw)

Biological Psychiatry, 1990

Abstract

ABSTRACT Examined potential relationships between human leukocyte antigens (HLAs), including the DR series, and depression in 19 depressed female patients (mean age 49.9 yrs) and 49 hypersomniac male and female patients (mean age 38.5 yrs). Frequency of HLA-DR5 was significantly increased in both depressed and hypersomniac Ss, providing support for the notion of a possible link between these conditions. Results also suggest that HLA-DR5 antigen may be more frequent in a subgroup of familial and recurrent depressive patients. (PsycINFO Database Record (c) 2012 APA, all rights reserved)

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