A journy through malaria research.pdf (original) (raw)

Analysis of Fifty Years of Severe Malaria Worldwide Research

Pathogens

This study analyzed fifty years of severe malaria research worldwide. Malaria is a parasitic disease that continues to have a significant impact on global health, particularly in sub-Saharan Africa. Severe malaria, a severe and often fatal form of the disease, is a major public health concern. The study used different bibliometric indicators such as the number of publications, citations, authorship, and keywords to analyze the research trends, patterns, and progress made in the field of severe malaria. The study covers the period from 1974 to 2021 and includes articles from Scopus. The results of the study indicated that there has been a steady increase in the number of publications on severe malaria over the past fifty years, with a particular increase in the last decade. The study also showed that most of the publications are from USA and Europe, while the disease occurs in Africa, South-East Asia, and the Americas. The study also identified the most frequent keywords used in the ...

Malaria: A Changing Scenario from the Past to the Future

Research and Reviews: Journal of Microbiology and Biotechnology, 2015

Malaria is a vector borne disease is the deadly most important life threatening diseases around the world, According WHO estimates that malaria kills about 660000 people per year. In the present commentary discussion about the focusing on malaria status from the past to the future and need of vaccination rather work on the anti malarial drugs which may results side effects.

Malaria: Cause and Control

Malaria is an endemic tropical disease caused by the haemosporidian blood parasite of the genus Plasmodium. The human variant of this infection is caused by four members of this genus: P. falciparum, P. vivax, P. ovale and P. malariae, with P. falciparum malaria infection responsible for the most lethal form of the disease. The disease accounts for over 500 million acute clinical episodes annually and over 1 million deaths, particularly among children below the age of four years; with other debilitating effects in pregnant women. The economic impact of malaria infection has been put conservatively at over US$1.8 billion annually and it is the eighth most important disease in terms of lost disability adjusted life years (DALYS). This review addresses the current state of knowledge on the epidemiology/epidemio-logical patterns, economic impacts of malaria on populations and communities, vector ecology and transmission dynamics, pathogenesis and pathogenic outcomes of this disease and global malaria eradication and control efforts. It also recommends the way forward in the unending battle between man, his environment and a determined parasite that has so far eluded the human quest to conquer and eradicate it.

Malaria in the 21st century - still a threatening problem

Srpski arhiv za celokupno lekarstvo

There are six parasite species (P. falciparum, P. vivax, P. ovale curtisi, P. ovale wallikeri, P. malariae, and P. knowlesi) that cause malaria in humans. P. falciparum is responsible for most malaria-related deaths globally. P. vivax is the dominant malaria parasite in most countries outside of the Sub-Saharan Africa. In 2016, 91 countries reported a total of 216 million cases of malaria. The global tally of malaria deaths reached 445,000. In 2016, 24 cases of imported malaria were registered in the Republic of Serbia, with an incidence of 0.33/100,000. According to the World Health Organization recommendations, every suspected malaria case should be confirmed by microscopy or a rapid diagnostic test before treatment. The main stone of antimalarial therapy should be artemisinin-based combinations. Since malaria occurs in Europe as an imported (though rarely also autochthonous and a hospital-borne infection), the objective of this paper is to point out current problems and attitudes...

Malaria: global challenges for malaria eradication

Microbiology Australia, 2016

The enormous decline in the annual morbidity and mortality from malaria is the spectacular global public health success of the past decade. This achievement results largely from increased finance for investment in measures known to prevent malaria: bednets treated with long-lasting insecticides, chemoprophylaxis, and rapid access to effective treatment. Such has been the success of these measures that plans are being put in place to achieve the vision of a malaria-free world within the next three decades. Large financial and political commitments and ongoing research will be required to maintain the gains, overcome known and unknown challenges such as drug and insecticide resistance, and to achieve those goals. Effective vaccines or methods for reducing mosquito vectorial capacity would add enormously to the chance of achieving this goal. The aim of this article is to summarise the current status of malaria control, the recent research successes, the challenges being addressed, and ...

Malaria research, 1980–2004, and the burden of disease

Acta Tropica, 2008

Malaria is estimated to cause about 1.6% of the 57 million deaths occurring annually and 2.3% of the disease burden. However, it accounts for only about 0.4% of world biomedical research, and this percentage is barely changing. Most of the research takes place in Europe and North America, which are little affected directly by the disease, 90% of whose burden occurs in sub-Saharan Africa. Research includes both pharmaceutical and non-pharmaceutical approaches; the fastest growing ones involve the artemisinins and genetics. Leading countries in malaria research (including India, Thailand, Kenya and Nigeria) differ greatly in the subjects that they favour.

Malaria: The Past and the Present

2019

Malaria is a severe disease caused by parasites of the genus Plasmodium, which is transmitted to humans by a bite of an infected female mosquito of the species Anopheles. Malaria remains the leading cause of mortality around the world, and early diagnosis and fast-acting treatment prevent unwanted outcomes. It is the most common disease in Africa and some countries of Asia, while in the developed world malaria occurs as imported from endemic areas. The sweet sagewort plant was used as early as the second century BC to treat malaria fever in China. Much later, quinine started being used as an antimalaria drug. A global battle against malaria started in 1955, and Croatia declared 1964 to be the year of eradication of malaria. The World Health Organization carries out a malaria control program on a global scale, focusing on local strengthening of primary health care, early diagnosis of the disease, timely treatment, and disease prevention. Globally, the burden of malaria is lower than ...

Burden of Malaria - A Journey Revisited

Scholars Journal of Applied Medical Sciences

Malaria has been one of humanity’s oldest and deadliest diseases. Despite gains over the first 15 years of this millennium, malaria control has stagnated in the last several years, with resurgence and rising morbidity in several highly endemic countries exacerbated by service disruptions due to the COVID-19 pandemic. Malaria imposes great socio-economic burden on humanity, and with six other diseases (diarrhea, HIV/AIDS, tuberculosis, measles, hepatitis B and pneumonia), accounts for 85% of global infectious disease burden. Malaria is caused by the bite of an infected, female, Anopheline mosquito. Mosquito is at the root of several vector borne diseases including malaria. The mechanism of spread of malaria in the human body has been well studied. Symptoms show up based on the type of organism involved in infection. Eradication of malaria and related diseases depends on eradication of the mosquito. Treatment options involve drugs, natural and synthetic, of which chloroquine occupies ...