Depression and depressive symptoms in rheumatoid arthritis patients: an analysis of their occurrence and determinants. (original) (raw)
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Symptoms of Depression and Disability among Rheumatoid Arthritis Patients
2020
Background Rheumatoid arthritis (RA) is a significant and serious public illness affecting peoples especially adults all over the world and emotional problems such as depressive symptoms are more common in patients with RA than in general population. Synovial inflammation, joint damage, degeneration of cartilage, bony destruction and limitation of physical functioning are the distinctive feature of RA that consequently leads to functional disability. This study aimed at assesses prevalence of symptoms of depression and disability among RA patients. Research Design: A descriptive correlational research design was utilized in this study. Study subjects: Established diagnosed 80 RA patients were included in the study. Two tools were used; Beck Depression Inventory (BDI) version I to assess symptoms of depression, and Health assessment questionnaire-disability index (HAQ-DI) to assess disease-related disability. Result: Majority of the participants were females with the age of (20-65) y...
The occurrence of depressive symptoms in rheumatoid arthritis: A cross-sectional study
Vojnosanitetski pregled, 2022
Background/Aim. Depression, as a common comorbidity in patients with rheumatoid arthritis (RA), has been found to affect the disease diagnosis and treatment response. Accordingly, the aim of the study was to investigate the occurrence of depressive symptoms among patients with RA and the association between RA and depression. Methods. The cross-sectional study included 69 patients with RA. The depressive symptoms in patients with RA were assessed using the Beck Depression Inventory (BDI), and RA activity was measured by Disease Activity Score-28 for RA with erythrocyte sedimentation rate (DAS28-ESR) and Clinical Dis-ease Activity Index (CDAI). Results. It was found that 42% of respondents reported having depressive symptoms of different severity, among which the majority (23.2%) presented with mild symptoms. A mild positive correlation was found between the BDI and the DAS28-ESR (r = 0.39 p = 0.001), as well as between the BDI and the CDAI (r = 0.40 p = 0.001). Place of residence (t...
Depression in patients with rheumatoid arthritis: description, causes and mechanisms
International Journal of Clinical Rheumatology, 2011
Two sets of contributory factors to depression among patients with rheumatoid arthritis (RA) are generally examined-the social context of the individual and the biologic disease state of that person's RA. This article will review the evidence for both. RA affects patients both physically and psychologically. Comorbid depression is common with RA and leads to worse health outcomes. Low socioeconomic status, gender, age, race/ethnicity, functional limitation, pain and poor clinical status have all been linked to depression among persons with RA. Systemic inflammation may also be associated with, cause, or contribute to depression in RA. Understanding the socioeconomic factors, individual patient characteristics and biologic causes of depression in RA can lead to a more comprehensive paradigm for targeting interventions to eliminate depression in RA.
Depression in rheumatoid arthritis: A re-evaluation
Rehabilitation Psychology, 1991
Diagnosing mood disorders in chronic illness is problematic. Understanding the value of individual symptoms in predicting depression is one approach to this problem. The contribution of individual symptoms to the diagnoses of major depressive disorder (MDD) was examined in 82 patients with confirmed rheumatoid arthritis (RA) and a control sample of ISO university employees. Comparisons between DSM-HI and DSM-EQ-R rates of MDD were derived using the Inventory to Diagnose Depression (IDD). It was found that cognitive-affective symptoms such as dysphoric mood, acknowledgment of guilt, and suicidal ideation were the most efficient predictors of MDD. According to DSM-IH-R criteria, 16% of the RA sample met criteria for diagnosis of MDD, while 27% of the R A sample met criteria according to the DSM-1H. RA patients reported that their arthritis affected their mood at least occasionally.
Depression in Rheumatoid Arthritis and its relation to disease activity
Pakistan Journal of Medical Sciences, 1969
Objectives: To determine the level of depression in Rheumatoid Arthritis and its relationship with severity of Rheumatoid Arthritis. Methods: This cross sectional analytical study was conducted from March 2014 to May 2014. Total 102 cases of Rheumatoid Arthritis (RA) diagnosed as per ACR (American College of Rheumatology) 1987 criteria were enrolled from Rheumatology Department, Fatima Memorial Hospital. Severity of Rheumatoid Arthritis was assessed by Health Assessment Questionnaire (HAQ) and disease activity score (DAS-28) while severity of depression was measured by Beck Depression Inventory (BDI) scale II questionnaire. The relationship between depression and disease activity (severity) of Rheumatoid Arthritis was assessed by calculating correlation coefficient between depression, disease activity score (DAS 28) of Rheumatoid Arthritis and health assessment questionnaire (HAQ). Results: Out of 102 patients, 77(75.5%) were females and 25(24.5%) males. The mean age of patients was 43.5± 11.9 years and the mean duration of disease was 7.8 ± 5.5 years.71.5% of Rheumatoid Arthritis patients were found to have some degree of depression and this was directly related to the severity of disease. Moderate and severe depression were present in 23 (22.5%) and 19(18.6%) patients respectively. Conclusion: In this study, almost three-fourths of Rheumatoid Arthritis patients were found to have depression. There was a strong association between Rheumatoid Arthritis disease activity and the level of depression. So it is imperative for clinicians treating Rheumatoid Arthritis patients to screen them for co morbid depression and manage it accordingly.
Factors of depression among patients with rheumatoid arthritis
Rheumatology, 2018
ObjectivesThe aim of this study was to assess the correlation between symptoms of depression and the course and clinical picture of rheumatoid arthritis (RA).Material and methods120 patients with RA were included in the study: 104 (87%) female patients and 16 (13%) male patients. All studied patients completed the following questionnaires: Beck Depression Inventory (BDI), Ford Insomnia Response to Stress Test (FIRST), Athens Insomnia Scale (AIS) and Health Assessment Questionnaire (HAQ). The serum levels of IL-1b, TNF-, and IL-6 were measured using standard ELISA assays at the time of the first questionnaire assessment.ResultsSymptoms of depression were found in 91 patients (76%), including 79 (87%) women and 12 (13%) men. There were no significant differences between the prevalence of depression in women and men (p = 0.93). Symptoms of depression occurred more often in patients who were professionally inactive, compared with the professionally active patients (p = 0.04). Significa...
Association of depression and rheumatoid arthritis
Orthopaedic Nursing, 2003
This study assessed the relative strength of the association of physical characteristics and social stresses with a diagnosis of depression in patients with rheumatoid arthritis. Depression and social difficulties were assessed in 74 patients with rheumatoid arthritis by using standardized research interviews. Rheumatoid arthritis activity, damage related to rheumatoid arthritis, and subjective functional disability were assessed with well-validated methods. Twenty-nine patients (39.2%) were depressed. Compared to nondepressed patients, depressed patients had more marked social difficulties related to rheumatoid arthritis (72.4% versus 46.7%, respectively) and more marked social difficulties independent of rheumatoid arthritis (55.2% versus 31.1%, respectively). With logistic regression, social difficulties, independent of rheumatoid arthritis, was the only variable significantly associated with depression. Demographic characteristics and rheumatoid arthritis were not associated with a diagnosis of depression. Recognition by clinicians of the importance of social stresses, independent of disease state, should lead to more appropriate and specific psychological and social treatment of depression in rheumatoid arthritis.
“The Rate of Depression in Knee Arthritis Patients: An Observational Study”
2021
INTRODUCTION: Pain is always a great dilemma in the world of medicine and chronic pain is becoming a major challenge globally at all level of care. Depression impact on physical behavior and may result in reduced movement, a deconditioning of the body, loss of natural endorphins and increasing levels of pain. METHODOLOGY: The study sample consists of 22 subjects having a chronic arthritis of knee patients with depression at the age between 45 to 65 years. The subjects who met the inclusion criteria were included in this study. Inform and written consent was taken from the subjects. Scale for depression also taken as a outcome measure. RESULT: Outcome measurement was measured using ces-d scale and seen that 41% subjects suffered from severe depressive symptomatology. CONCLUSION: The study concludes that depression is significant in knee arthritis patients. This questionnaire can be used as screening tools in knee arthritis patients. These will affect the burden on the cost of quality...
Depressive symptoms in early rheumatoid arthritis: a comparative longitudinal study
Clinical Rheumatology, 2007
Our objective was to investigate symptoms of depression in early rheumatoid arthritis (eRA) patients, and follow them longitudinally during a 3-year prospective study of 73 Hungarian and 45 Austrian early rheumatoid arthritis patients. Compared to validated national population data, mild symptoms of depression were detected in Hungarian early rheumatoid arthritis patients, which were independent of corticosteroid use. In the Hungarian subgroup, the Beck Depression Inventory scores were found to be stable during follow-up. Except at the baseline visit, depressive symptoms and functional status, as measured by the Health Assessment Questionnaire, were correlated. Significant differences were detected between Austrian and Hungarian patients despite of their geographical and cultural proximity. The mean depression score was higher in the Hungarian when compared to the Austrian patients. Depression is an important feature of early rheumatoid arthritis. Studies assessing depression in rheu-matoid arthritis patients must be based on validated national data of normal population.
Clinics (São Paulo, Brazil), 2015
Rheumatoid arthritis (RA) is a costly and crippling autoimmune disease that can lead to the development of depression, contributing to suboptimal clinical outcomes. However, no longitudinal studies have identified an association between rheumatoid arthritis and subsequent depression. This study aimed to investigate the incidence and risk factors of depression among RA patients in Taiwan. Using Taiwan's National Health Insurance Research Database, we identified 3,698 newly diagnosed RA patients aged 18 years or older, together with 7,396 subjects without RA matched by sex, age and index date, between 2000 and 2004. The incidence of depression and the risk factors among RA cases were evaluated using Cox proportional-hazard regression. The incidence of depression was 1.74-fold greater in the RA cohort than in the non-RA cohort (11.80 versus 6.89 per 1,000 person-years; p<0.01). Multivariate analysis showed that RA subjects who were female, were older, or had comorbidities such a...