Ocular Lymphoma: Clinical, Diagnostic, and Therapeutic Aspects (original) (raw)
Ocular involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an in-traocular manifestation of systemic lymphoma. Lymphoma manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis , uveitis, multiple evanescent white dot syndrome, acute retinal necrosis, or herpetic retinitis. Accurate diagnosis depends on a high index of suspicion and frequently requires histopathological analysis of specimens, particularly vitreous biopsy, subretinal aspiration, or retinal biopsy with flow cy-tometry, polymerase chain reaction, or immunohistochemistry methods. Most of ocular lymphomas are of B lineage. Diagnosis is often complex and needs use of paraclinical evaluations. Treatment mainly consists of chemotherapy. It is important to review the ocular manifestations of lymphoma to assist oph-thalmologists in prompt diagnosis of ocular lymphoma. And it also helps oncologists to recognize the need for a complete oph-thalmic evaluation in the diagnosis, follow-up, and management of patients with lymphoma. Iran J Med Sci 2008; 33(4): 195-201. Keywords ● B cell lymphoma ● tumor ● lymphoma ● eye neoplasm ● intraocular
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