IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from human marginal zone B cells as well as from circulating peripheral blood B cells from autoimmune patients (original ) (raw )IL-21 modulates cytokine levels in murine collagen-induced arthritis and contributes to disease pathology
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Arthritis Research & Therapy, 2007
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Arthritis & Rheumatism, 2007
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Journal of Experimental & Clinical Medicine, 2014
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Arthritis Research & Therapy, 2007
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Arthritis & Rheumatism, 2009
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Arthritis Research & Therapy, 2007
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F1000 - Post-publication peer review of the biomedical literature, 2014
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IL-21R deficiency during experimental arthritis increases local expression of inflammatory mediators but protects against joint pathology by suppressing Th17 cells
Renoud Marijnissen
Annals of the Rheumatic Diseases, 2010
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Peter van Lent
PLOS ONE, 2017
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A Positive Feedback Loop of IL-21 Signaling Provoked by Homeostatic CD4+CD25- T Cell Expansion Is Essential for the Development of Arthritis in Autoimmune K/BxN Mice
Eunkyeong Jang
The Journal of Immunology, 2009
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Active immunization against IL-23p19 improves experimental arthritis
Luca Semerano
Vaccine, 2011
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Thomas Kamradt , Anne Taubner
Arthritis Research & Therapy, 2007
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Increased Interleukin 21 (IL-21) and IL-23 Are Associated with Increased Disease Activity and with Radiographic Status in Patients with Early Rheumatoid Arthritis
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The Scientific World JOURNAL, 2007
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Inflammation In Vivo and In Vitro Roles of IL-21 in
Denis Girard
2004
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Mesenchymal stem cell repair capabilities are defective in rheumatoid arthritis in relation with in vivo exposure to inflammation
Elena Jones
Arthritis Research & Therapy, 2007
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Activation of synovial fibroblasts by laminin-1 and transforming growth factor beta induces expression of stromelysins independently of TNFα, IL-1β or NF-κB
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Arthritis Research & Therapy, 2007
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Ioannis Alexiou
Arthritis Research & Therapy, 2007
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In vivo and in vitro roles of IL-21 in inflammation
Denis Girard
The Journal of Immunology, 2004
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Investigation of the role of the p38 MAPK α and δ isoforms in nonresponse to tumour necrosis factor blockade in the synovium of rheumatoid arthritis patients
Paul Emery
Arthritis Research & Therapy, 2007
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Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis
Louis Boon
Arthritis & Rheumatism, 2010
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Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production
Thiago Cunha
2016
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Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation
Leo Joosten
Arthritis & Rheumatism, 2011
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Importance of CD23 for Collagen-Induced Arthritis: Delayed Onset and Reduced Severity in CD23-Deficient Mice
Birgitta Heyman
The Journal of Immunology, 1999
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Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthritis
Steffen Gay
Annals of the Rheumatic Diseases, 2008
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Changes and significance of IL-25 in chicken collagen II-induced experimental arthritis (CIA)
siamak sand
Rheumatology international, 2012
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Peroxisome proliferator-activated receptor gamma 1 expression is diminished in human osteoarthritis cartilage and is downregulated by IL-1β in articular chondrocytes
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Arthritis Research & Therapy, 2007
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Cytokines (IL-15, IL-21, and IFN-γ) in rheumatoid arthritis: association with positivity to autoantibodies (RF, anti-CCP, anti-MCV, and anti-PADI4) and clinical activity
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Clinical Rheumatology, 2019
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Nitric oxide differentially regulates T-cell function in rheumatoid arthritis and systemic lupus erythematosus
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Arthritis Research & Therapy, 2007
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