Patients with epilepsy and patients with psychogenic non-epileptic seizures: Video-EEG, clinical and neuropsychological evaluation (original) (raw)
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2018
Objective: To Study the Clinical, Psychological and Neurological Profile and Assessing the Outcome Predictors of Patients with Psychogenic Non Epileptic Seizures in North Indian adult population. Design of study: A prospective observational study, conducted at tertiary teaching institute at Jaipur. Materials and Methods: Seventy-four patients with PNES were enrolled. The diagnosis was based on mobile recordings of episodes, and video-electroencephalography (video-EEG) monitoring. A detailed clinical evaluation was done including evaluation for coexistent anxiety, depression or other psychiatric disorder. Patients were followed-up to 2 months. Statistical Analysis: Appropriate statistical tests were used. Results: The mean age at onset was 22 years; with female to male ratio were 17.5:1.Coexisting epilepsy was present in 6 (8.10%).40 patients(54.05%) had received one or multiple antiepileptic drugs. Out of 74 patients of PNES 48(64.86%) had predominant motor phenomenon, whereas 26 pa...
Archives of Neuroscience
Background: Both epileptic seizures (ES) and psychogenic non-epileptic seizures (PNES) are often associated with some degree of cognitive impairment. Video electroencephalography (EEG) monitoring is the gold standard for diagnosing PNES. This diagnostic procedure is costly and available in specific tertiary centers. Neuropsychological assessment can provide clues for the differential diagnosis of PNES and ES and help clarify the nature and etiology of these two disorders. Objectives: Therefore, this study aimed to compare the neuropsychological profiles of PNES and ES patients. Methods: In this analytical cross-sectional study, 30 patients with ES and 31 patients with PNES were compared by neuropsychiatric tests, such as the Wechsler Adult Intelligence scale (WAIS), Addenbrooke’s Cognitive examination (ACE), and California Verbal Learning test (CVLT). Results: There was a female predominance in the PNES group (female-to-male ratio = 4.16/1, P = 0.003). In the PNES group, 77.4% of th...