Role of calcitonin (Ct) in wash-out fluid from fine-needle aspiration (FNAB) in the diagnosis of medullary thyroid cancer (MTC): comparison with basal calcitonin, cytology and pentagastrin stimulation test (Pg-Test) (original) (raw)

2010

Abstract

Results: Ct-FNAB levels in nodules with MTC or C-Cells Hyperplasia (CCH) was significantly (P< 0.0001) higher than in hyperplastic nodules and than serum Ct (P= 0.02). The sensitivity and the specificity for basal Ct were 100 and 18.2% respectively. The sensitivity for Pg-test resulted 100%, and the specificity 95.4%. Cytology sensitivity was very low (10%) with a specificity of 95.4%. The ROC curves showed that both Ct-FNAB and Pg-test to correctly distinguish MTC or CCH nodules from hyperplastic nodules better than ...

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