Maternally-inherited Leigh syndrome-related mutations bolster mitochondrial-mediated apoptosis (original) (raw)

A second missense mutation in the mitochondrial ATPase 6 gene in Leigh's syndrome

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Annals of Neurology, 1993

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Leigh disease presenting in utero due to a novel missense mutation in the mitochondrial DNA–ND3

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Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism

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Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA

Susana Gamen

1996

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Mutant NDUFS3 subunit of mitochondrial complex I causes Leigh syndrome

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Italian Journal of Neurological Sciences - ITAL J NEUROL SCI, 1999

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Mitochondrial disease associated with the T8993G mutation of the mitochondrial ATPase 6 gene: a clinical, biochemical, and molecular study in six families

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Lack of apoptosis in mitochondrial encephalomyopathies

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Acta Neurologica Scandinavica, 2006

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Cary Harding

Pediatric Neurology, 2001

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Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

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