Hormonal profile of infertile Makkans (original) (raw)
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The Correlation between the Abnormal Hormonal Assay and Infertility among Saudi Males
Clinical Medicine and Diagnostics, 2013
Semen analysis and hormonal evaluations are prerequisite in the assessment of infertile men. The object ive of this study is to evaluate the hormonal parameters of in fertile men in Saudi Arabia, results fro m one centre. Materials and methods included clinical data and laboratory work fro m a sample of 235 infert ile Saudi men were reviewed. Results showed that hormonal evaluation revealed high level of FSH (57.4 %), normal level of LH (61%), testosterone (67.7%) and prolactin (83%) in the study population. To conclude, further studies are required in order to determine causes of high prevalence of endocrine abnormalities in infertile men in Saudi Arabia.
Physiological Study of the Gonadotropic Hormones Role on The Male Infertility in Thi-Qar Province
JOURNAL OF COLLEGE OF EDUCATION FOR PURE SCIENCE, 2019
This study was designed to Identify the role of hormones profile such as Gonadotropic hormonesof male infertile in Thi-Qar Province through the assessing of gonadotropic hormones which is responsible for infertility occurring. A 200 blood serum samples were collected from the patients at the Infertility Unit who directly deal with infertility and other 100 blood serum samples collected too from healthy people. The hormones were Evaluated from the two serum sets and tested hormones by technology of using a sandwich immunodetection method. Results noticed that the highest percentage (11%) of serum hormones low levels of Gonadotropic hormones (Test., LH. &FSH.) for Oligozoospermia and Azoospermia equality, therefore it was observed significant difference between hormones levels of infertile groups compared with control at (p≤0.05).
International Journal of Scientific Research in Biological Sciences, 2018
we assessed the serum levels of Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Testosterone (T) which are the principle hormones responsible for the control of spermatogenesis. A total of 125 married men facing fertility problem and 35 proven fathers were assessed for the serum hormone levels and the sperm count, attending a tertiary infertility center in North Karnataka. Statistical analysis of different variables were performed using SPSS 20.0. Significant reduction in mean sperm count and increased Luteinizing Hormone levels among cases was found (p <0.05). There was an insignificant difference between the mean serum levels of Follicle Stimulating Hormone and Testosterone of the cases to that of the control group (p = 0.191, p = 0.228). The current study found significant correlation of Sperm count with serum Follicle stimulating hormone and (p = 0.014) and insignificant correlation with Luteinizing hormone (p = 0.523) and Testosterone (p =-0.078) among cases.
Impact of Serum Prolactin and Testosterone Levels on Male Infertility in Sulaimanyah City
Mosul Journal of Nursing
The appropriateness of the interactions between Prolactin, gonadotrophins and testicular hormones ensures that normal spermatogenesis takes place in the male. So this study is an attempt to classify male infertility depending on WHO criteria of seminal changes and to evaluate serum Prolactin, Testosterone FSH and LH levels in the participants, also determine the association between serum Prolactin, Testosterone levels and subtypes of male infertility. This study involved three hundred infertile males having infertility more than one year (cases group) and three hundred age-matched fertile males with definite paternity in past two years (control group) were included to the study from Jan 2018-Dec 2020 at Shahid Ali Qader consultant clinic in the Sulaimanyah city. Serum levels of hormones were measured by electrochemiluminescense immunoassay technique. Approximately half of patient's age ranged between 30-39 years. Sixty eight percentage of cases complained from primary infertility. About 71.3% of patients had infertility duration between 1-5 years. This percentage decreased with increasing the infertility years. Most common infertile group was Asthenospermia (34.3%). A higher significant levels of serum Prolactin, FSH and LH found in cases than controls (p<0.001). However, the serum Testosterone levels was significantly lower in cases than controls (p<0.05). Moreover, serum Prolactin levels were found significantly elevated in all infertile subgroups (except Normospermic subgroup) compared to control group, while serum Testosterone levels were significantly decreased in all infertile subgroups (except Normospermic subgroup) compared to control group (p<0.05). So we conclude that; Poor spermatogenesis is associated with high serum Prolactin, FSH,LH levels and low serum Testosterone levels in patients with male infertility. Moreover, elevated serum Prolactin levels and decreased serum Testosterone levels were significantly associated with A, AT, OAT, Azoo and OA infertile males.
Study of Thyroid Hormones in Male Infertility
2018
DOI: 10.21276/sjams.2018.6.9.66 Abstract:Hormones are one of the principal factors in intercellular and inter-organ communication. The thyroid hormones are crucial for normal functioning because of their control over body’s basal metabolic rate, as well as growth, development, and differentiation of many cells/organs in the body.The present study was based on a crosssectional study design carried out at the outpatient department of Maheshwara Medical College & Hospital from January 2017 to July 2018. Serum levels of free thyroxin (FT4), thyroid stimulating hormone (TSH), free testosterone, prolactin (PRL), folliclestimulating hormone (FSH), and luteinizing hormone (LH) were measured using immunoassay commercial kits in both groups. The normal reference ranges for thyroid hormones were as follows: TSH, 0.3 to 5.0 IU/mL and T4, 4.5 to 12.5 g/dL. Erectile dysfunction was evaluated using International Index of Erectile Function (IIEF-5) questionnaire. The results were averaged as (mean ...
European Journal of Obstetrics & …, 2003
Objective: To analyse the factors predisposing to male immunological infertility from the hospital records of 508 patients that had been treated for infertility in the Turku University Central Hospital from 1980 to 2000. In addition, the hormonal status was investigated at the beginning of treatment. Results: Patients with a history of mumps, or either a fresh varicocele or a history of varicocele had statistically significant lower levels of MAR antisperm antibodies (ASAs) than patients with no such conditions. Repair of varicocele (either surgical or embolisation), showed a statistically significant enhancement of the total sperm cell counts in ejaculates, but it appeared not to have any influence on other parameters of the semen analysis (mobility and morphology). Of all male infertility patients, 66.3% had normal hormonal status at the beginning of treatment, 12.6% of patients had hypotestosteronemia and 22.1% had subclinical hypogonadism. Patients with subclinical hypogonadism had lower total sperm cell count in ejaculates than patients with normal hormonal status although they had statistically significant more offspring. In addition, it appeared that mumps orchitis as well as smoking and alcohol abuse are risk factors for subclinical hypogonadism. Conclusion: No clear predisposing factor for male immunological infertility could be found. However, patients with subclinical hypogonadism differed from other male infertility patients and thus may form a special group among the male infertility patients.
Measuring some hormonal Levels of infertile women in Samarra city - Iraq
IOP Conference Series: Materials Science and Engineering, 2018
Population-based on infertility data collecting from a woman with thyroid gland diseases or sub-clinical thyroid (hyperthyroidism and hypothyroidism) in Samarra city. Thus, the plan was to search about thyroid status and some hormone levels in infertility woman. The aim of the study was to determine the levels of LH, FSH, TSH, T3, T4 from the serum of infertile women in Samarra city, and to explain the relationship between hormone levels and the probability to cause infertility. The results showed a significant difference at (P≤ 0.05) between levels of LH of infertile women as compared with intact group. The results also showed a significant difference at (P<0.05) of (TSH, T3, T4) of infertile women as compared with intact; there were no significant differences at (P<0.05) of (FSH) level between infertile women & intact.
Investigation of Thyroids Dysfunction Among Infertile Women in Nasiriyah City
International Journal of Current Pharmaceutical Research, 2020
Objective: Epidemiological studies revealed that 10-15 % of couples in the world experience infertility. Thyroid dysfunction (hyperthyroidism and hypothyroidism) possessed adverse effect on reproductive health and resulted in, interference with ovulation, reduced rates of conception, increased early pregnancy loss, and adverse effects on pregnancy and neonatal outcomes. The current study aims to explore the thyroid dysfunction among infertile women in Nasiriyah city-Iraq. Methods: The study was conducted on 60 infertile women (age group 17–45 y) who visited infertility departments in Al-Hussein hospital, Al-Haboubi hospital and Bent AL Huda hospital, in Nasiriyah city, from October 2019 to March 2020. Thirty normal females (age matched) were taken as controls. TSH, T3, T4, LH, FSH, prolactin, progesterone and estradiol levels were determine by using VIDAS® Assay. Results: The prevalence of hyperthyroidism among infertile women was 13.33% and hypothyroidism was 10.00%. Both hyper and...
Hormonal Profile of some Infertile Women in Bida Nigeria
Background and Aim: The desire for reproduction is a basic human instinct, and it is well known that infertility is one of the psychosocial problems affecting many couples worldwide. The aim of this study is to evaluate the hormonal profile of infertile women in Bida metropolis. Materials and Methods: A total of 200 individuals comprising of 160 infertile and 40 fertile women as controls were recruited into this cross‑sectional study in Bida metropolis, Nigeria. Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), progesterone, and estradiol were determined using enzyme immunosorbent assay. Results: Infertile women had significantly higher LH and PRL level (P < 0.05) and statistically lower progesterone and estradiol level (P < 0.05) when compared to fertile women. There was no significant difference in FSH level of infertile women (P > 0.05) when compared to fertile women. Nonmenstruating women (NMW) had lower FSH and progesterone level (P < 0.05) and significantly higher PRL and estradiol level (P < 0.05) when compared to MW. There was no significant difference in LH level of NMW (P > 0.05) when compared to MW. Hormonal abnormalities were observed in 83.3% of the infertile women. This comprises of 30% secondary hypogonadism, 20% hyperprolactinemia/hypogonadism, 13.3% primary hypogonadism, 13.3% hyperestrogenemia, and 6.7% hyperprolactinemia. Conclusion: This study has shown that infertility remains a major problem affecting women of childbearing age. It is therefore recommended that couples should seek medical care on time as well as determine their hormonal status to correct any abnormality that might have arisen.
Thyroid Profile in Primary Infertility-Study at A Tertiary Care Hospital in Telangana
SSR Institute of International Journal of Life Sciences, 2024
Background: In the condition of primary hypothyroidism, the levels of thyrotropin-releasing hormone (TRH) are higher to raise thyroid-stimulating hormone (TSH) levels, causing hyperprolactinemia, oligomenorrhea, and anovulation. Hypothyroidism may result in miscarriage, premature birth, and neurodevelopmental deformities. Thyrotoxicosis is also associated with spontaneous abortions, risk of congenital anomalies, and aplasia cutis. The present study primarily focuses on studying thyroid hormones in female infertility. Methods: The current study was a cross-sectional investigation conducted on individuals attending outpatient departments (OPD) after considering the inclusion-exclusion criteria. Euthyroid, Primary hypothyroid, Primary hyperthyroid, Secondary hypothyroid, Secondary hyperthyroid, Subclinical hypothyroid, and Subclinical hyperthyroid were the seven characteristics that were used to classify the total number of patients that were included in the study. Results: After the data has been thoroughly obtained, it is recorded into tables with the appropriate titles using Microsoft Excel software. According to the findings of our analysis, there is no correlation between age and thyroid function in groups. Our research findings show no statistically significant link between age and thyroid health across all categories (p>0.05). Conclusion: With our study, we can propose thyroid supplementation in subclinical hypothyroidism for treating infertile women. Simultaneously, females with marginal levels of TSH shall not be ignored in infertile women, which may lead to asymptomatic subclinical hypothyroidism. It can be concluded that thyroid dysfunction is related to primary infertility in females. Hence, primary infertility may be better studied with a large sample size and long-term follow-up to confirm our findings further.