Contact Lens Induced Corneal Ulcer Management in a Tertiary Eye Unit in Oman - A descriptive study (original) (raw)
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Journal of Young Pharmacists, 2021
Objectives: To study the current practice patterns and opinions in the treatment of corneal bacterial ulcers among Saudi ophthalmologists. Methods: A web-based online survey was conducted in Saudi Arabia to randomly selected ophthalmologists who were registered with Saudi commission for health specialties during the study period between August 2018 to December 2018 using a structured self-administered questionnaire. Results: Of the respondents, general ophthalmologists were 32 (58.2%) and cornea specialists were 23 (41.8%). The mean years of practice was 6.6±6.1 [mean±SD]. Among the respondents 53 (96.4%) treated corneal ulcer cases, most of them 51 (92.7%) agreed there is a relation between the use of contact lenses and ocular ulcers. Fifty respondents indicated that they prescribed antibiotics for the treatment of corneal ulcer. About 12 (52.2%) of the cornea specialist and 22 (68.8%) of general ophthalmologists prefer to use culture of ulcer (Scrapping and gram staining of ulcer)...
Acta Ophthalmologica Scandinavica, 2006
Purpose: To evaluate the clinical and epidemiological aspects of contact lensrelated infectious corneal ulcers requiring hospitalization. Methods: A retrospective analysis was performed on the files of patients hospitalized for contact lens-induced corneal ulcer in the eight Belgian university hospitals over a 7-year period (January 1997 to December 2003. Diagnoses for all hospitalized patients are obligatorily registered using the ICD-9 code. Results: A total of 107 patients with contact lens-related corneal ulcers were documented: the number increased from five in 1997 to 22 in 2003. A total of 99 subjects used soft contact lenses, of whom nine used disposables, 73 planned replacement and 17 conventional lenses. Only six patients used extended wear lenses. Three patients used daily disposable lenses. The most frequently cultured organisms were Pseudomonas and other Gram-negative germs (70%) and Acanthamoeba (16%). The majority (77%) of the corneal ulcerations were centrally located and resulted in an average visual loss of four lines. Conclusion: During the study period, the number of patients hospitalized rose, which is only partially explained by the increasing prevalence of lens wearers: 3.5% and 6.5% of the Belgian population used lenses in 1995 and 2003, respectively. These factual data highlight the need for improvements in patient education.
Good Outcome of Corneal Ulcer With Hypopion After Long Use of Contact Lens
Vision Science and Eye Health Journal
Introduction: Microbial keratitis is a corneal infection caused by microorganisms and is characterized by a profound corneal epithelial defect that infects the cornea and causes severe and progressive visual loss. In recent years, the incidence of microbial keratitis has increased. One of the critical risk factors for increasing this incidence is using contact lenses. As the number of contact lens users increases, the number of corneal ulcers associated with contact lenses also increases. Case Presentation: A 25-year-old man was admitted to the emergency department with a complaint of gradually blurry vision in his left eye four days after using contact lenses for overnight uses since the previous few days and did not routinely clean contact lenses or replace contact lens cleaning fluid. The visual acuity of the patient's left eye was hand movement with conjunctival and pericorneal injection in the conjunctiva and 6 x 7 mm stromal level infiltrate, blurred margin, and whitish co...
International Journal of Medical Research and Review
Introduction: Corneal ulcer is one of the common reasons for ophthalmic OPD and IPD visit. It is responsible for vision loss in large number of patients. We have conducted this study to evaluate epidemiological characteristics, predisposing factors and treatment outcome of corneal ulcer patients in tertiary care teaching hospital. Method: A prospective study of corneal ulcer patients from Dec 2009 to Nov 2013 was done. Data related to socio-demography, predisposing factors, prior treatment and duration of symptoms were recorded. Ulcer was evaluated by slit lamp examination. Corneal scrapings were subjected to Gram`s stain and 10% KOH wet mount. Results: 432 eyes were evaluated. 53.9% were between 26-45 yrs.71.06% eyes presented with vision <3/60. Trauma was commonest factor found in 53.93% patients. On staining 22.9% were having fungal and 64.12% mixed bacterial and fungal infection. Anatomically 34.7% completely recovered leaving scar. 3 eyes were eviscerated, rest not completed treatment. Conclusion: Corneal ulcer is common eye problem in developing countries. Most of ulcers were moderate to severe grade. Treatment given on the basis of basic laboratory investigations and clinical features was effective in about 84% of patients. Severe consequences can be prevented by community based awareness.
Contact lens–related corneal ulcers in compliant patients
American Journal of Ophthalmology, 2004
PURPOSE: To report a case series of contact lens-related corneal ulcers in compliant patients with no apparent predisposing factors. DESIGN: Retrospective case series. METHODS: Charts of 70 patients with contact lens-related corneal ulcers from July 1999 to June 2002 were reviewed. Lens care hygiene and method of disinfection, as well as frequency of lens replacement, were recorded. Only patients who followed recommended guidelines for contact lens wear were included in the study. RESULTS: Of the 70 patients, 21 (30%) developed corneal ulcers despite being compliant with the guidelines for contact lens wear. All patients used multipurpose solutions for cleaning, disinfecting, and storing daily wear soft contact lenses. CONCLUSION: Standard lens care hygiene does not seem to be sufficient in preventing the development of corneal ulcers in patients using conventional and frequent replacement daily wear soft contact lenses.
Current Trend of Corneal Ulcer In Patients Attending a Tertiary Healthcare Centre
2016
Purpose: To study the epidemiological characteristics and etiology of corneal ulcer at a tertiary healthcare centre of upper Assam. Materials and Methods: The present prospective hospital based study was carried out on 60 consecutive corneal ulcer cases attending outpatient and admitted in in-patient department of ophthalmology, Assam Medical College. After clinical and slit-lamp biomicroscopic examination, corneal scrapings were collected from all the corneal ulcer cases and subjected to microscopy and culture. Results: Out of 60 consecutive patients having keratitis, 37 (61.66%) were found to be culture positive. Rate of detection of bacterial, fungal and mixed growth were respectively 32.43%, 59.48% and 5.40%. Patients from rural background constitute 71.6% (43).Ocular trauma 51 (85%) was the most common predisposing factor followed by acute and chronic dacryocystitis 4 (6.66%) and diabetesmellitus 3(5%) . Bamboo stick injuries accounted for 19(37.25%) cases followed by injuries ...
Corneal Ulcer and Adverse Reaction Rates in Premarket Contact Lens Studies
American Journal of Ophthalmology, 1991
We analyzed clinical data on 22,739 contact lens wearers who were studied and whose lenses were approved under 48 manufacturersponsored studies for the Food and Drug Administration between 1980 and 1988. The incidence of corneal ulcers was low in the cosmetic (nontherapeutic) daily-wear soft and rigid gas-permeable lens wearers (1/1,923 and 1/1,471 patient-years, respectively). Corneal ulcers and severe adverse reactions occurred two to four times more frequently in extend ed-wear cosmetic soft and rigid gas-perme able lens wearers than in cosmetic daily-wear lens wearers. Aphakic extended-wear soft lens users were nine times more likely to develop a corneal ulcer when compared to the soft daily-wear cosmetic group. Corneal abra sions and keratitis accounted for 81 of 159 severe adverse reactions, whereas corneal ul cers accounted for 28 of 159 adverse reactions. The data indicate that overnight extended wear of contact lenses is associated with a greater risk of serious, sight-threatening com plications than daily wear.
Clinical Evaluation of Corneal Ulcer among Patients Attending Teaching Hospital
Introduction: To effectively prevent blindness in patients with corneal ulcer, a proper understanding of risk factors pre-disposing to ulceration, and clinical and microbial characteristics of the disease is essential. Aim is to know the age and sex distribution of corneal ulcer. To identify the predisposing factors, etiological factors contributing to corneal ulcer. To study the clinical features and management of corneal ulcer. Material and methods: Study was undertaken among 80 patients who were diagnosed to have corneal ulcers for a period of 1 year. This is an observational study to identify the common etiological agents, predisposing factors, age, gender, and occupational distribution and to study the clinical features.
Ulcerative Keratitis in Contact Lens Wearers
Eye & Contact Lens: Science & Clinical Practice, 2003
To determine the clinical microbiological characteristics of corneal ulcers in contact lens wearers. Methods: A retrospective study of 23 patients admitted to our department with contact lens-related corneal ulcers during a 43-month period. Detailed demographic data, the type of contact lens, duration of lens wear, and wearing schedule were derived from a self-administered questionnaire. The severity of the ulcer; cultures of corneal scrapings, storage solutions, and contact lenses; treatment; and final outcome were evaluated. Results: Of the 86 cases of ulcerative keratitis admitted during the study period, 23 (26.74%) were attributed to contact lens use. Most patients were young women from urban areas. All of them were using soft contact lenses for 3 days to 20 years. Five patients used daily-wear lenses as extended-wear lenses. Most ulcers (47.82%) were mild; 30.43% were moderate; and 21.47% were severe. Corneal scrapings for cultures were obtained in 15 of the cases and were positive in 10 (43.47%) of them, whereas in 33.33% of the culture-positive storage solutions and in 66.67% of the culture-positive contact lenses, corneal scrapings were negative. Pseudomonas aeruginosa was the most frequent isolated pathogen (60%). The final visual acuity was 20/40 or better in 60.87% of the cases. Conclusions: Contact lens use is an important risk factor for the development of ulcerative keratitis, with P. aeruginosa remaining the predominant pathogen. It seems important to culture contact lenses and contact lens storage solutions, in addition to the corneal scrapings, and the role of initial therapy for the corneal ulcers remains important.