Breast Lumps Presenting During Pregnancy (original) (raw)
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Radiologic Evaluation of Breast Disorders Related to Pregnancy and Lactation
RadioGraphics, 2007
Note: This copy is for your personal non-commercial use only. To order presentation-ready copies for distribution to your colleagues or clients, contact us at www.rsna.org/rsnarights. Breast Disorders Related to Pregnancy and Lactation Benign disorders closely related to physiologic changes Gestational and secretory hyperplasia Spontaneous bloody nipple discharge Galactocele Gigantomastia Inflammatory and infectious diseases Puerperal mastitis Granulomatous mastitis Mastopathic disease Juvenile papillomatosis Benign tumors Tumor closely related to pregnancy and lactation Lactating adenoma Morphologic and physiologic changes in fibroadenomas secondary to pregnancy and lactation Growing fibroadenoma Fibroadenoma with infarction Fibroadenoma with secretory hyperplasia or lactational change Malignant tumors PABC PABC in BRCA germline mutation carriers Pregnancy-related Burkitt lymphoma of the breast
Nodular breast lesions during pregnancy and lactation
Histopathology, 1993
A review of the clinical and pathological features of 30 lactating nodules which were retrieved over the period 19 75-1 99 1 was undertaken. Clinically, the nodules occurred during any pregnancy and in subsequent pregnancies no further nodules developed. There were no favoured sites or lateralization of nodules, nor was there any correlation between nodule occurrence and ethnic background. Morphologically, a pre-existing underlying lesion was readily recognized in 1 8 cases. Seven fibroadenomas, five tubular adenomas, two of which were infarcted, and six breast hamartomas were identified. The other 1 2 cases were well circumscribed nodules with a variable degree of inflammation and lobular hyperplasia. It is best to recognize these lesions as a heterogeneous group and designate them as lactating nodules, noting any underlying pathological process rather than using the older term lactating adenoma which implies a single neoplastic entity.
Study of clinical, imaging and pathological assessment of breast lumps: an observational study
International Surgery Journal
Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclu...
Breast Lump- a Clinicopathological Study
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Breast lumps are showing a rising trend nowadays. Heightened anxiety associated with breast lump and its classification into benign and malignant is necessary. Seeing the burden of disease and rising trend of malignancy, our study aimed to document the spectrum of breast lump at
Pregnancy related breast diseases in a developing African country: initial sonographic evaluation
Pan African Medical Journal, 2015
Benign diseases are more common than malignant diseases in pregnant and lactating women. Fibroadenomas are the most commonly identified benign breast tumour in pregnant and lactating women. Pregnancy related breast cancer is defined as breast cancer that occurs during pregnancy or within 1 year of delivery. Its incidence is estimated at 1 in 3000 to 1 in 10 000 pregnancies. Several reproductive factors like age at menarche, age at menopause, age at full-term pregnancy, parity, age at any birth and spacing of pregnancies, breast feeding, characteristics of the menstrual cycle, infertility, spontaneous and induced abortions, characteristics of the menstrual cycle and infertility are some of the factors that have been incriminated as risk factors for breast cancer. We sought to describe the predominant breast pattern, sonographic array of pregnancy related breast diseases in women referred to the breast imaging unit in the department of Radiology at the University College Hospital, Ibadan south west Nigeria. Socio-demographic characteristics in these women were also evaluated. Archived images were reviewed and documented and data was analysed with SPSS version 17 and presented with descriptives. In this descriptive study, we retrospectively retrieved the sonomammographic records of 21 women (pregnant or lactating) referred to and imaged in the department of radiology, University college hospital Ibadan, between 2006 and 2013. Diagnostic breast sonograms performed by MO and ATS; Consultant radiologists with 7-10 years' experience utilized a 7-10 MHz transducer of the General electric GE Logiq P5 machine for the scans. Twenty-one women with ages between 22-42 years (Mean 31.4 ±5.4 SD) pregnant or lactating were referred to the radiology department for sonomammographic evaluation. Majority of the women were in the 3rd decade. Referral was mainly (11) by family Physicians from the general outpatient clinic, 5 were self-referred, 2 from radiotherapy department, 2 from obstetrics and gynaecology department and 1 from the surgical outpatient clinic. Nineteen (89.5%) were lactating and breastfeeding while 2 (10.5%) were pregnant. Nipple discharge (89.5%) was the predominant presenting complaint in the study. They were all married with the majority attaining menarche at age 14.6±2.1 SD years. Most of the women were multi-parous 17(89.5%) and possessed higher level of Education 17 (81.0%). Twenty (96.0%) women had no previous breast disease while only 1 (4.0%) woman had a positive family history of breast cancer. They weighed between 44-102kg (mean 69.84kg±15.33SD). Their mean height was 159.8cm. Waist hip ratio was between 0.69-0.93 (Mean 0.83). The heterogeneous fibroglandular pattern was predominant in 15 (71.4%) women. Final BIRADS assessment of 2 was most frequent (11/21) 52.4% while 19.0% were assigned to BIRADS categories 0 and 1 (4/21). Histological diagnosis of Invasive ductal carcinoma was made in the 3 women with final BIRADS of 5 breast diseases found in most pregnant and lactating women were benign. It is important to note that malignant breast lesions can also occur in this group of women who may assume that the changes noted in their breast are due to lactation.
American Journal of Roentgenology, 2013
The purpose of this article is to review key clinical, histologic, and imaging features of pregnancy-associated breast cancer. A discussion of imaging modalities, including mammography, ultrasound, and MRI, and imaging-based interventions available for evaluating this population is provided. CONCLUSION. Successful detection of pregnancy-associated breast cancer requires knowledge of key clinical and imaging features of pregnancy-associated breast carcinoma and selection of the appropriate imaging workup and intervention. Vashi et al. Breast Imaging of the Pregnant and Lactating Patient Women's Imaging Clinical Perspective tages of ultrasound include safety secondary to its lack of ionizing radiation and a high sensitivity in the detection of pregnancy-associated breast cancer. Despite generalized nodularity of the breast on physical examination during pregnancy and lactation, all patients with a dominant palpable breast mass that persists for 2 weeks or longer should be evaluated with a targeted ultrasound examination [2] (Fig. 1). The utility of ultrasound in detecting malignant lesions in these patients has been well established, with studies reporting 100% sensitivity [3-6] and 100% negative predictive value [3] for pregnancy-associated breast carcinoma. Moreover, ultrasound can detect most benign breast masses in these patients. Any suspicious mass identified on ultrasound can be promptly evaluated with ultrasound-guided core needle biopsy, although most biopsies performed will yield benign results. If a highly suspicious breast mass is found or if core needle biopsy results are positive for malignancy, evaluation of the ipsilateral axilla as well as bilateral wholebreast ultrasound should also be considered. Identification of a suspicious axillary lymph node or of clinically occult multifocal (in the same quadrant), multicentric (in a different quadrant), or contralateral disease may facilitate prompt and efficient preoperative staging. Because patients with pregnancy-associated breast cancer may present with more locally advanced disease than nongestational patients, neoadjuvant chemotherapy may be appropriate. In these cases, serial ultrasound examinations have been shown to be useful