original ) (raw )Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients
Pärt Peterson
Frontiers in immunology, 2014
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Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
Ola Winqvist
Human Molecular Genetics, 2002
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Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
Séverine Ménoret
The Journal of Immunology
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Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen Su , Paula Bubulya , Karen Giang
Journal of Clinical Investigation, 2008
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Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma
Björn Rozell
Blood, 2006
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Beyond APECED: An update on the role of the autoimmune regulator gene (AIRE) in physiology and disease
Francesco Indiveri
Autoimmunity Reviews, 2018
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RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
Stylianos Antonarakis , Kai Krohn , H. Scott , P. Naquet
European Journal of Immunology, 2000
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Gene Dosage-limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity
Daniel GRAY
Journal of Experimental Medicine, 2004
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Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)
Elizaveta Fasler-kan
The Journal of Immunology, 2000
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AIRE and immunological tolerance: insights from the study of autoimmune polyendocrinopathy candidiasis and ectodermal dystrophy
Fabio Buzi
Current Opinion in Allergy and Clinical Immunology, 2004
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A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery
Hamish Scott
The Journal of Immunology, 2008
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Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator
Ola Winqvist
European Journal of Immunology, 2006
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Autoimmune Regulator Is Expressed in the Cells Regulating Immune Tolerance in Thymus Medulla
Kai Krohn
Biochemical and Biophysical Research Communications, 1999
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Genetic Basis of Altered Central Tolerance and Autoimmune Diseases: A Lesson from AIRE Mutations
emilia cirillo
International Reviews of Immunology, 2012
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Faculty of 1000 evaluation for Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
Andrea Sant
F1000 - Post-publication peer review of the biomedical literature, 2004
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Aire and T cell development
Maureen Su
Current Opinion in Immunology, 2011
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Autoimmune regulator: from loss of function to autoimmunity
Pärt Peterson
Genes & Immunity, 2003
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A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire
Klaus Rajewsky
European Journal of Immunology, 2017
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Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
Hamish Scott
The Journal of Immunology, 2009
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A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Joonas Joensuu
Journal of immunology (Baltimore, Md. : 1950), 2007
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Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients
Mohammad Alimohammadi
Journal of Autoimmunity, 2006
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Reduced Thymic Aire Expression and Abnormal NF- B2 Signaling in a Model of Systemic Autoimmunity
Maree Hammett , Richard Boyd
The Journal of Immunology, 2009
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AIRE expression controls the peripheral selection of autoreactive B cells
Eric Meffre
Science Immunology
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The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function
Sharad Purohit
The Journal of Immunology, 2007
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AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies
Pärt Peterson
Cell, 2016
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Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype
Simon Forehan
The Journal of Immunology, 2009
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Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
Pärt Peterson
Nature Reviews Immunology, 2008
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