Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase (original) (raw)
Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme
Eva Johansson
FEBS Journal, 2007
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Significance of the O-Helix Residues of Escherichia coli DNA Polymerase I in DNA Synthesis: Dynamics of the dNTP Binding Pocket †
Virendra Pandey
Biochemistry, 1996
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Electrostatic guidance of catalysis by a conserved glutamic acid in Escherichia coli dTMP synthase and bacteriophage T4 dCMP hydroxymethylase
Larry Hardy
Biochemistry, 1995
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Kinetic Characterization of dUTPase from Escherichia coli
Jan-Olov Kvassman
Journal of Biological Chemistry, 1996
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Tyr254 Hydroxyl Group Acts as a Two-Way Switch Mechanism in the Coupling of Heterotropic and Homotropic Effects in Escherichia coli Glucosamine-6-phosphate Deaminase †
E. Horjales
Biochemistry, 1998
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Christopher Thibodeaux
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Dehydration of Ribonucleotides Catalyzed by Ribonucleotide Reductase: The Role of the Enzyme
Pedro Fernandes
Biophysical Journal, 2006
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Rafik Karaman
Journal of the American Chemical Society, 1992
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Henry Miziorko
Biochemistry, 2012
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MRN Murthy
Journal of Biological Chemistry, 2006
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Structural Basis for Recognition and Catalysis by the Bifunctional dCTP Deaminase and dUTPase from Methanococcus jannaschii
John Tainer
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Possible role of two phenylalanine residues in the active site of human cytidine deaminase
Silvia Vincenzetti
Protein Engineering, Design and Selection, 2000
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The Structure of the Cytidine Deaminase−Product Complex Provides Evidence for Efficient Proton Transfer and Ground-State Destabilization † , ‡
Charles Carter
Biochemistry, 1997
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Characterization of Mutants of βHistidine91, βAspartate213, and βAsparagine222, Possible Components of the Energy Transduction Pathway of the Proton-Translocating Pyridine Nucleotide Transhydrogenase of Escherichia coli
Philip Bragg
Archives of Biochemistry and Biophysics, 2001
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Steady-State Kinetics and Molecular Evolution of Escherichia coli MenD [(1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase], an Anomalous Thiamin Diphosphate-Dependent Decarboxylase−Carboligase
Milan Bhasin
Biochemistry, 2003
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Catalytic conformation of carboxypeptidase A
Devkumar Mustafi
Journal of Molecular Biology, 1983
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Selenomethionine substitution of orotidine-5′-monophosphate decarboxylase causes a change in crystal contacts and space group
Jens-christian Poulsen
Acta Crystallographica Section D Biological Crystallography, 2001
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Use of a purified heterodimer to test negative cooperativity as the basis of substrate inactivation of Escherichia coli thymidylate synthase (Asn177→ASP)
Larry Hardy
Structure, 1994
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Structure of Escherichia coli dGTP Triphosphohydrolase: A Hexameric Enzyme With DNA Effector Molecules
Alejandro Hochkoeppler, Mark Itsko, Damian Gawel
The Journal of biological chemistry, 2015
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Crystal Structures of the Binary Ca2+ and pdTp Complexes and the Ternary Complex of the Asp21 .fwdarw. Glu Mutant of Staphylococcal Nuclease. Implications for Catalysis and Ligand Binding
Eaton Lattman
Biochemistry, 1994
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Functional Implications of Second-Shell Basic Residues for dUTPase DR2231 Enzymatic Specificity
Cristiano Mota
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Allosteric Effects of Nucleotide Cofactors on Escherichia coli Rep Helicase&DNA Binding
Timothy Lohman
Science, 1992
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Steady-State Kinetics and Molecular Evolution of Escherichia coli MenD [(1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase], an Anomalous Thiamin Diphosphate-Dependent Decarboxylase−Carboligase
Milan Bhasin
Biochemistry, 2003
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Structural Determinants of Oligomerization of Δ1-Pyrroline-5-Carboxylate Dehydrogenase: Identification of a Hexamerization Hot Spot
Ranjan Singh
Journal of Molecular Biology, 2013
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Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding
Apostolos Gittis
Biochemistry
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Mutagenesis and Reversion Analysis of Residue Met-209 of the β-Subunit ofEscherichia coliATP Synthase
Janet Pagan
Archives of Biochemistry and Biophysics, 1995
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Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV)
Mary Ondrechen
Environmental and Molecular Mutagenesis, 2012
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Reaction of 1-Amino-2-methylenecyclopropane-1-carboxylate with 1-Aminocyclopropane-1-carboxylate Deaminase: Analysis and Mechanistic Implications †
Huawei Chen
Biochemistry, 2003
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The Effect of Hinge Mutations on Effector Binding and Domain Rotation in Escherichia coli D-3-Phosphoglycerate Dehydrogenase
Sanghamitra Dey
Journal of Biological Chemistry, 2007
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The Role of Conserved Histidine Residues in the Pyridine Nucleotide Transhydrogenase of Escherichia Coli
Philip Bragg
European Journal of Biochemistry, 1996
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Molecular mimicry in deoxy-nucleotide catalysis: the structure of Escherichia coli dGTPase reveals the molecular basis of dGTP selectivity
Jinhu Song
2018
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Structural Analysis of 1-Aminocyclopropane-1-Carboxylate Deaminase: Observation of an Aminyl Intermediate and Identification of Tyr 294 as the Active-Site Nucleophile
Qin Zhou
Angewandte Chemie International Edition, 2004
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Localization of the site for the nucleotide effectors of Escherichia coli carbamoyl phosphate synthetase using site-directed mutagenesis
Vicente Fresquet
FEBS Letters, 1999
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Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity
Jane Grasby
Nucleic Acids Research, 2001
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