Effect of antibiotic prophylaxis on the risk of surgical site infection in orthotopic liver transplant (original) (raw)

This study investigates the incidence, timing, location, and risk factors associated with surgical site infections (SSI) in orthotopic liver transplant recipients, particularly focusing on the effect of antibiotic prophylaxis. Conducted as a prospective multi-center study across 11 hospitals in Spain, the research identifies key pathogens responsible for SSIs and highlights significant risk factors including the type of surgery performed and the duration of blood transfusions. Findings suggest that specific antibiotic regimens, such as glycopeptide/aztreonam, are associated with a markedly lower incidence of SSI.