Barun Kant Dixit Prevalence of Thyroid Disorders in Population of Moradabad (original) (raw)

Estimation of Thyroid‑Stimulating Hormone Level in Normal College Female Students in a Semi‑Urban Indian Town: Kumbakonam Urban‑Rural Epidemiological Study‑ KURES – 7

medknow , 2020

Background: Subclinical hypothyroidism (SCH) is a biochemical disease which is characterized by elevated serum levels of thyroid stimulating hormone (TSH) with normal thyroid hormone levels. In an attempt to correct the disease at its entry point, we wished to find out the incidence of subclinical hypothyroidism in female college students in Kumbakonam, a semiurban town of India. Methods: Around 260 female college students who had no history of thyroid disease were screened for thyroid dysfunction by a TSH assay. Results: The mean age ± standard deviation was 18.72 ± 2.27 years. The mean TSH value was 3.98 mIU/mL. The incidence of abnormally high TSH values was around 11.5%. The number of such cases was 30 with low T3 values in six students. One had a value of 150 with no symptoms. Another student had a value of 0.15 and her T3‑T4 profile was normal. All students were asymptomatic. None of the students had goiter. Conclusions: In an unpublished but accepted study, we found an incidence of 3.5% in the school female children in the age group of 15–17. A sudden jump in the incidence is occurring in the age group of 18–22. This needs a workup of the causative factors and their possible correction

Thyroid Function Status in Indian Adult Nonpregnant Females in Ranchi, India

Indian Journal of Medical Biochemistry

Aim Thyroid disorders are one of the most common endocrine diseases in India. Thyroid disorders are more common in women than in men and contribute to significant morbidity. In this postiodization era, there is paucity of pan-Indian data of thyroid disorder status among adult nonpregnant women. This study was done to analyze the thyroid hormone levels in women of Jharkhand region, which is traditionally known to be an iodine-deficient area. Materials and methods Three hundred and forty nonpregnant adult females in Ranchi area who were consuming iodized salt formed part of the study group. Clinical evaluation was done by a gynecologist pertaining to thyroid illness. Thyroid function tests encompassing triiodothyronine, thyroxine, and thyroid-stimulating hormone were carried out by quantitative enzyme immunoassay method. Thyroid status of the population was defined as per kit reference range. Results Subjects with age range 20 to 67 years were divided into three groups as per clinical...

Spectrum of Thyroid Disorders In Bankura District, West Bengal, India: A Cross-Sectional Observational Study

2020

Thyroid disorders are the most common endocrine diseases in India. Numerous studies in various countries differ in their prevalence rate for both hypothyroidism and hyperthyroidism. This present crosssectional observational study was conducted in Bankura Sammilani Medical College, Bankura, West Bengal to find out the prevalence of thyroid disorders among the people of this district. This present study was done over 700 patients, attending hospital suspected of having thyroid disorders, were screened for thyroid function. Serum samples were taken and serum Thyrotrophin (TSH) and free tetraiodothyronine (fT4) were estimated by ELISA method. Of this 700 study subjects, 17.14% were found to have thyroid dysfunction; among them, 7.43% had subclinical hypothyroidism, 5.57% had overt hyperthyroidism and 4.14% were suffering from hyperthyroidism. Females were affected more in both hypothyroidism and hyperthyroidism than males. The age group of 21-30 years was affected more than the others in all types of thyroid disorders.

Estimation of Prevalence and Patterns of Thyroid Dysfunction in a Tertiary Care Centre in Uttarakhand, India: A Cross-sectional Study

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Introduction: Thyroid dysfunction is a common endocrine disorder, defined as the altered serum Thyroid Stimulating Hormone (TSH) levels with normal or altered FT3 and FT4 (triiodothyronine and thyroxine) levels. The spectrum of thyroid disorders includes hypothyroidism, hyperthyroidism, goiter/ iodine deficiency disorders, autoimmune thyroiditis, thyroid cancer, as well as subclinical hypothyroidism or hyperthyroidism. However, further research is required on the spectrum of thyroid disorders, apart from goiter/iodine deficiency disorders in the study population mentioned. Aim: To investigate the prevalence and patterns of thyroid disorders in the clinical biochemistry laboratory of a tertiary care hospital in the hilly region of Uttarakhand, India. Materials and Methods: Present cross-sectional study was conducted in the clinical biochemistry laboratory of Veer Chandra Singh Garhwali (VCSG) Govt. Institute of Medical Science and Research Centre, Srinagar Garhwal, Uttarakhand, India...

Hospital Based Study of Thyroid Disorders in Rural Population of Gurgaon, Haryana

International journal of current research and review, 2016

Introduction: Endocrine disorders pose a major threat to public health. Current research shows that 300 million people are suffering from thyroid disorders globally and 42 million among them reside in India. Objective: Our objective is to find the prevalence of thyroid disorders in rural population of Gurgaon, Haryana. Materials and Methods: This study was conducted in SGT Medical College & Hospital, Budhera, Gurgaon, Haryana from January, 2015 to July, 2016. 3940 patients were screened for thyroid function. Thyroid function was assessed by quantitative estimation of T3 (Triiodothyronine), T4 (Thyroxine) and TSH (Thyroid Stimulating Hormone) in serum by chemiluminscent immuno assay. Results: The prevalence of thyroid disorder was found to be 25.17% (992) in the study population. 74.82% (2948) patients were euthyroid. Among the thyroid dysfunction patients 16.85% (665) belonged to hypothyroidism group (11.70% primary, 3.20% sub clinical and 3.24% clinically euthyroid) and 8.29% (327)...

A Study on Prevalence of Thyroid Function Disorders Amongst The Population of Barpeta District, Assam

IOSR Journal of Dental and Medical Sciences, 2017

Introduction and objectives-Thyroid diseases are amongst the commonest endocrine disorders worldwide. India too is no exception. In India sub Himalayan belt extending from Kashmir to Assam is well a recognized area of endemic iodine deficiency. The main aim of the study was to find out the prevalence of thyroid disorders amongst the adult population of Barpeta town and to create awareness among the population about the disorder. Material and methods-The current study was a cross sectional study conducted in the Barpeta district, Assam at Fakhruddin Ali Ahmed Medical College and Hospital. 600 participants were included in the study after taking proper consent after explaining the procedure to each subjects. Assays for thyroid hormones (T3 ,T4) and TSH were performed by Electrochemiluminescence(ECL) technology using Immunoassay analyzer Roche Cobas e411. Anti TPO antibodies were also measured by the same analyzer. The prevalence of different thyroid function disorders was summarized as count and percentages. A chi square test was used to assess the trends in the prevalence of the disorders among different age groups and genders. Result-Of the total study population 443 (73.83%) subjects had normal levels of serum T3, T4 and TSH values without history of thyroid medication. Other 157 (26.17%) subjects had abnormal serum thyroid hormones and TSH levels, who were categorized as hypothyroid, subclinical hypothyroid, hyperthyroid and subclinical hyperthyroid. The prevalence of hypothyroidism in the overall study population was 9.67 %(n=58) , of which6.33%(n=20) were self reported cases and 6.33%(n=38) were previously undetected. Subclinical hypothyroidism was observed in 4% of the study population. Hyperthyroidism-a total of 25 (4.17%) participants including 14 females were diagnosed with hyperthyroidism. Subclinical hyperthyroidism was seen in 10 subjects including 6 female subjects though significant association between the frequency of the disorder with age or gender was not seen. Anti TPO antibody positivity was seen in 40 subjects without significant variation as per gender and age. Conclusion-Our study demonstrates that hypothyroidism was higher in the older adults with a female preponderance and there is a significant prevalence of hyperthyroidism too.

A hospital-based study of prevalence of thyroid dysfunction in Srinagar, Jammu and Kashmir state of India

International Journal of Medical Science and Public Health, 2014

Background: Significant incidence of thyroid dysfunction, especially hypothyroidism, has been reported in Kashmir Valley of India. There is a paucity of studies that assessed the presence of thyroid dysfunction in various age groups of people in Srinagar. Objectives: This study aimed to investigate the prevalence of thyroid dysfunction in the local population who visit the outpatient department of Ramakrishna Mission Clinic at Srinagar. Materials and Methods: This work is a cross-sectional study carried out for 18 months. The study subjects were the patients who attended outpatient department of Ramakrishna Mission Clinic; patients referred by private practitioners of Srinagar and adjoining areas. The data were from those subjects who got thyroid function tests done for the first time. Thyroid function was assessed by clinical examination and thyroid function tests (T3, T4, and TSH). Results: The total number of subjects tested for thyroid function was 612 of which 120 were men and 492 were women. Total prevalence of thyroid disorders in the study population was 40.36% (247 of 612). Of the total 247 subjects with thyroid disorders, 17.8% were men (44) and 81.2% were women (203). Overall prevalence of subclinical hypothyroidism was 33% (206 of 612); prevalence of overt hypothyroidism was 5% (31 of 612); and prevalence of hyperthyroidism was 1.6% (10 of 612). Conclusion: There is a high prevalence of thyroid disorders in Kashmir population, and subclinical hypothyroidism is the most prevalent thyroid disorder. In females, maximum prevalence of subclinical hypothyroidism is seen in the reproductive age group.

Prevalence of Thyroid Dysfunction in Community of Duwakot, Bhaktapur

Journal of Pathology of Nepal

Background: Thyroid dysfunction is one of the major public health problems in the Nepalese community and of the common endocrine disorders diagnosed in community primary health care centres. The aim of this study is to analyze the prevalence of Thyroid dysfunction in Duwakot, Nepal. Materials and Methods: All the patients from Duwakot community who presented with the history of weight gain with tiredness and weight loss with palpitation were subjected to thyroid function test free triiodothyronine, free thyroxine and thyroid stimulating hormone. Results: Thyroid dysfunction was found in 26% with M:F ratio of 1:5. Subclinical hypothyroidism 62 (11.44%) was the most prevalent one followed by Primary hypothyroidism 48 (8.85%), primary hyperthyroidism 16 (2.95%) and subclinical hyperthyroidism 15 (2.76%). Conclusion: Thyroid dysfuntion has been observed despite of nationwide program regarding supplementation of micronutrient iodised salt.

Thyroid Dysfunction in General Population of Khyber Pakhtunkhwa, Pakistan

Pakistan Journal of Medical Sciences, 1969

Objectives: The objective of this research was to elucidate some of the major relation of thyroid dysfunctions, keeping in view the various selected demographic details of included patients. Methods: This study was approved by the ethical committee of Post Graduate Medical Institute (PGMI) Hayatabad Medical Complex Peshawar, and was conducted in the Institute of Radioactive Nuclear Medicine (IRNUM) Peshawar. The blood samples were collected, followed by their analysis for triiodothyronine (T 3), tetraiodothyronine (T 4) and thyroid stimulating hormone (TSH). Results: The results obtained regarding the demographical aspects of the patients revealed that female gender has categorically significantly high percentage of occurrence of thyroid abnormality as compared to male gender (75.8% vs. 24.2%). Results regarding locality distribution of the patients depicted that majority of those belonged to the local population of Peshawar and Charsadda region. Conclusion: In Pakistan especially Khyber Pakhtunkwa (KPK), thyroid diseases are more common in females as compared to males. The most probable causes could be lactation and pregnancy.

Estimation of Thyroid Stimulating Hormone Level in Normal Female School Children in A Semi Urban Indian Town -Kumbakonam Urban Rural Epidemiological Study- KURES -2

thyroid disorder school female , 2020

Symptoms of thyroid dysfunction are non-specific, yet common and hence screening for abnormalities becomes a necessity. To identify subclinical thyroid dysfunction and offer them the correct medical treatment especially in adolescent female children is an excellent option as a public health prophylactic measure. Hence in this study, we sampled 264 asymptomatic school female children for TSH and found an incidence of 3.4% of high TSH (>5). On the other side, the lower values were found in six (if TSH <0.5) or only two children (if TSH < 0.4). The mean with standard error of TSH values were 2.99 ±0.567. The fasting status was not complied with, and all were random blood samples. All children with abnormal results were counselled with parents and necessary medical advice given. This prevalence is the lowest among similar studies done in any Asian country which is a new finding in our study. Only one child showed a value of 150 who was given drugs and followed up. We theorize that this lesser incidence may be partly due to the study being done in a delta area of a semiurban town.