Farklı Süreli Yüzme Egzersizinin Sıçanlarda Serum Leptin ve Ghrelin Düzeylerine Etkisi (original) (raw)

Aim: The aim of this study was to investigate the effect of serum leptin and ghrelin in rats performing various duration swimming exercise. Material and Method: In the study, 30 healthy average weight of 180-220 grams albino wistar male rats were divided into 5 groups; control, water exercise, 15, 30 and 60 minutes swimming groups. Rats had been swim-exercised 15, 30 and 60 minutes/day for 90 days with. At the end of 90 days, after performed urethane (1.25 g/kg) anesthesia, blood samples were taken by intracardiac way. Collected blood was centrifuged quickly, and transferred to eppendorf tubes were stored in a freezer at -80°C for resulting serum biochemical analysis and leptin and ghrelin analyzed in accordance with the procedures. The data were analyzed using SPSS version 15 (Statistical Package for the Social Sciences). Results: Results showed that the leptin levels; control (1480,00 pg/ml), water exercise, (705,83 pg/ml), 15 (602,33 pg/ml), 30 (396,67 pg/ml) and 60 (435,83 pg/ml). Compared the control and 30 minutes swimming group (p<0.05, p=0.012), control and 60 minute swimming group (p<0.05, p=0.017), statistically significant correlation between them was determined. Results showed that the ghrelin levels on the groups; control (14,13 pg/ml), water exercise, (14,13 pg/ml), 15 (14,25 pg/ml), 30 (14,28 pg/ml) and 60 (14,26 pg/ml). İt is determined that there is no statistically significant correlation between groups on ghrelin (p>0,05). Conclusion: Different term (15,30,60 minute) of swimming exercise resulted decrease of the leptin levels and determined no changes in levels of ghrelin in rats. Anahtar Kelimeler: Ghrelin; Leptin; Rat; Swimming exercise.