One-Pot Four-Component Synthesis of Tetrasubstituted Pyrroles (original) (raw)

2008, Helvetica Chimica Acta

A convenient one-pot four-component synthesis of tetrasubstituted pyrroles was carried out through the reaction of butane-2,3-dione with a-aminophosphorous ylides, obtained in situ from the 1 : 1 : 1 addition reaction between triphenylphosphine, dialkyl acetylenedicarboxylate, and ammonium acetate.

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