IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers (original) (raw)
2010, The Journal of General Physiology
AI-generated Abstract
The study investigates IP3-dependent calcium transients induced by electrostimulation in adult skeletal muscle fibers. It demonstrates that the slow Ca2+ signals generated by electrical stimulation rely on dihydropyridine receptors (DHPR) and are mediated by IP3, with significant differences observed between fast and slow muscle fibers. The slow calcium signaling pathway is crucial for understanding excitation-contraction coupling and its implications in muscle physiology.
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