Targeting human telomerase for cancer therapeutics (original) (raw)

A highly selective telomerase inhibitor limiting human cancer cell proliferation

N. Kraut

The EMBO Journal, 2001

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A novel telomerase template antagonist (GRN163) as a potential anticancer agent

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Telomeres and Telomerase: Pharmacological Targets for New Anticancer Strategies?

Evelyne Ségal-Bendirdjian

Current Cancer Drug Targets, 2006

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Pharmacological intervention strategies for affecting telomerase activity: Future prospects to treat cancer and degenerative disease

János Aradi

Biochimie, 2008

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

Jerry Shay

Proceedings of the National Academy of Sciences, 1999

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Allosteric inhibitors of telomerase: oligonucleotide N3'->P5' phosphoramidates

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Therapeutic Anticancer Approaches Targeting Telomerase and Telomeres

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Alternative Approaches to the Discovery and Development of Telomerase- Targeted Anticancer Drugs

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Telomerase activity: An attractive target for cancer therapeutics

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Preclinical and clinical strategies for development of telomerase and telomere inhibitors

Elzbieta Izbicka

Annals of Oncology, 1997

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Novel Short Oligonucleotide Conjugates as Inhibitors of Human Telomerase

Jerry Shay

Nucleosides, Nucleotides and Nucleic Acids, 2003

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Oligonucleotides Targeting Telomeres and Telomerase in Cancer

nabiha khan

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TELOMERASE TARGETING IN CANCER

Hari Krishnan

International Research Journal of Modernization in Engineering Technology and Science, 2020

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Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach

SaeHeum Song

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Simultaneous Targeting of Telomeres and Telomerase as a Cancer Therapeutic Approach1

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Telomerase inhibition as cancer therapy

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Cancer letters, 2003

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Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors

Thomas Mürdter

Laboratory Investigation, 2005

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Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound

Sean Kerwin, Laurence Hurley

Journal of Medicinal Chemistry, 1997

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Synthesis and Human Telomerase Inhibition of a Series of Regioisomeric Disubstituted Amidoanthraquinones

HS Huang

Chemical and Pharmaceutical Bulletin, 2007

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Effect of Telomere and Telomerase Interactive Agents on Human Tumor and Normal Cell Lines

Elzbieta Izbicka

Clinical Cancer …, 2000

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Targeted Covalent Inhibition of Telomerase

Rama Mishra

2019

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Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA

Santanu Bhattacharya

Chemical Communications, 2014

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Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy

Hee-Sheung Lee

Cancer Research, 2018

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Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991

Hiroyuki Seimiya

Molecular cancer therapeutics, 2002

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