Generation of well-defined clickable glycopolymers from aqueous RAFT polymerization of isomaltulose-derived acrylamides (original) (raw)

Generation of well-defined clickable glycopolymers from aqueous RAFT polymerization of isomaltulose-derived acrylamides. Glycopolymers, which mimic natural polysaccharides, have significant implications in biology and material science due to their potential biocompatibility and ability to enhance carbohydrate-protein interactions. This work explores the efficient synthesis of these glycopolymers using the RAFT polymerization method, highlighting the development of 'clickable' glycomaterials which are advantageous for diverse applications. Key findings demonstrate the successful controlled polymerization at moderate temperatures, yielding polymers with well-defined structures and functionality, potentially paving the way for innovative applications in drug delivery and glycobiology.