Lymph node classification systems in cutaneous T‐cell lymphoma. Evidence for the utility of the working formulation of non‐Hodgkin's lymphomas for clinical usage (original) (raw)
in patients with uneffaced LN when classified according to the NCI-VA (LNO-2 versus LN3) or Dutch (GrO-1 versus Gr2) ratings. In addition, all classification systems demonstrated a poor survival time associated with effaced LN. By combining results from the modified Rappaport and Dutch classifications, three prognostic groups could be identified based on cell morphology: a low-grade category with a small cell histologic subtype (median survival time, 40 months); a high-grade immunoblastic subtype (median survival time, 9 months) composed of cells with an oval nucleus containing a large, usually solitary central nucleolus; and an intermediate-grade category composed of all cases without the distinctive small cell and immunoblastic morphologies (median survival time, 26 months).
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.