Can the abdominal perimeter be used as an accurate estimation of intra-abdominal pressure?* (original) (raw)

Acute neuro-endocrine profile and prediction of outcome after severe brain injury

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2013

Object: The aim of the study was to evaluate the early changes in pituitary hormone levels after severe traumatic brain injury (sTBI) and compare hormone levels to basic neuro-intensive care data, a systematic scoring of the CT-findings and to evaluate whether hormone changes are related to outcome.

Impact of Hemorrhagic Shock on Pituitary Function

Journal of the American College of Surgeons, 2015

BACKGROUND: Hypopituitarism after hypovolemic shock is well established in certain patient cohorts. However; the effects of hemorrhagic shock (HS) on pituitary function in trauma patients remains unknown. The aim of this study was to assess pituitary hormone variations in trauma patients with HS. STUDY DESIGN: Patients with acute traumatic HS presenting to our level 1 trauma center were prospectively enrolled. HS was defined as systolic blood pressure (SBP) ≤ 90 mm Hg on arrival or within 10 minutes of arrival in the ED, and requirement of ≥ 2 units of packed red blood cell transfusion. Serum cortisol and serum pituitary hormones [vasopressin (ADH), adrenocorticotrophic hormone (ACTH), thyroid stimulating hormone (TSH), follicular stimulating hormone (FSH), and luteinizing hormone (LH)]

Stress hormones inaccident patients studied before admission tohospital

1996

Objective-To assess stress hormone response in traumatised patients studied at the site of injury and on their way to hospital. Methods-The study was prospective. Blood samples were taken from 77 patients immediately after the arrival of the emergency physician at the site of the accident (tl) and shortly before patients' admission to hospital (t2). Plasma concentrations of 3 endorphin, cortisol, adrenocorticotrophic hormone (ACTH), prolactin, and growth hormone were measured. Results-Trauma in out-of-hospital patients resulted in remarkably increased concentration of growth hormone within minutes. ACTH, cortisol, and prolactin were only moderately increased. No significant correlations were found between hormone levels and blood pressure or heart rate. The plasma ACTH concentration was significantly lower before admission to hospital than immediately after the accident. Plasma cortisol, prolactin, and growth hormone concentrations were not significantly different between the two points of observation. In samples taken immediately after the accident (tl), there was a positive correlation between both , endorphin and prolactin and the injury severity score, whereas cortisol levels were negatively correlated with injury severity score, suggesting impaired cortisol release from the adrenal cortex after severe injury. At t1 ACTH was correlated with cortisol and (8 endorphin. Patients with head injuries had hormone concentrations similar to those without head injuries but with a similar injury severity score from injuries in other parts of the body. Conclusions-Lower cortisol concentrations in the very severely injured might be due to failure of the adrenal cortex to respond normally to ACTH stimulation. Growth hormone seems to play a major role in the response to trauma, reflecting an immediate stress response.