A Method for Designing Peptide Substrates for Proteases. Tripeptidyl-p-nitroanilide Substrates for Subtilisin Carlsberg
Marianne Pusztai-Carey
European Journal of Biochemistry, 1979
View PDFchevron_right
Polypeptide halomethyl ketones bind to serine proteases as analogs of the tetrahedral intermediate. X-ray crystallographic comparison of lysine- and phenylalanine-polypeptide chloromethyl ketone-inhibited subtilisin
Jens Birktoft
The Journal of biological chemistry, 1976
View PDFchevron_right
Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism
Dafydd Jones
Proceedings of the …, 2011
View PDFchevron_right
Importance of Tetrahedral Intermediate Formation in the Catalytic Mechanism of the Serine Proteases Chymotrypsin and Subtilisin
J. Malthouse
Biochemistry, 2012
View PDFchevron_right
Subtilisin-catalyzed hydrolysis of peptide methyl esters
Manfred Philipp
FEBS Letters, 1974
View PDFchevron_right
A highly active and oxidation-resistant subtilisin-like enzyme produced by a combination of site-directed mutagenesis and chemical modification
lene bech
European Journal of Biochemistry, 1990
View PDFchevron_right
A study of the unfolding of the inhibited subtilisin in guanidine hydrochloride
Richard Epand
International journal of peptide and protein research, 1975
View PDFchevron_right
Alteration of the specificity of subtilisin BPN' by site-directed mutagenesis in its S1 and S1' binding sites
Thomas Graycar
Journal of the American Chemical Society, 1991
View PDFchevron_right
Insights on activity and stability of subtilisin E towards guanidinium chloride and sodium dodecylsulfate
Danilo Roccatano
Journal of Biotechnology, 2014
View PDFchevron_right
Redesigning the reactive site loop of the wheat subtilisin/chymotrypsin inhibitor (WSCI) by site-directed mutagenesis. A protein–protein interaction study by affinity chromatography and molecular modeling
Augusto Parente
Biochimie, 2009
View PDFchevron_right
Modification of arginine residues in subtilisins Novo and Carlsberg
Krassimira Idakieva
International Journal of Peptide and Protein Research, 1983
View PDFchevron_right
The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 å resolution 1 1 Edited by I. A. Wilson
ujwal shinde
Journal of Molecular Biology, 1998
View PDFchevron_right
Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water
Lawrence Stern
Proceedings of the National Academy of Sciences, 1998
View PDFchevron_right
Complex between the subtilisin from a mesophilic bacterium and the Leech inhibitor eglin-C
Z. Dauter
Acta Crystallographica Section B Structural Science, 1991
View PDFchevron_right
Pro‐peptide as an intermolecular chaperone: renaturation of denatured subtilisin E with a synthetic pro‐peptide
Saburo Aimoto
Molecular Microbiology, 1991
View PDFchevron_right
Transformation of active-site lysine in naturally occurring trypsin inhibitors. A basis for a general mechanism for inhibition of proteolytic enzymes
Royce Haynes
Biochemistry, 1968
View PDFchevron_right
Structural Basis of Inhibition Revealed by a 1:2 Complex of the Two-headed Tomato Inhibitor-II and Subtilisin Carlsberg
Isabelle Barrette-Ng
Journal of Biological Chemistry, 2003
View PDFchevron_right
The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 å resolution1
ujwal shinde
Journal of Molecular Biology, 1998
View PDFchevron_right
Molecular dynamic study of subtilisin Carlsberg in aqueous and nonaqueous solvents
Gabriel Barletta
Molecular Simulation, 2009
View PDFchevron_right
Structural Basis for Dual-Inhibition Mechanism of a Non-Classical Kazal-Type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
Adrian Velazquez-Campoy
PLoS ONE, 2011
View PDFchevron_right
The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 å resolution
U. Shinde
Journal of Molecular Biology, 1998
View PDFchevron_right
Engineering Substrate Preference in Subtilisin: Structural and Kinetic Analysis of a Specificity Mutant †
Biao Ruan
Biochemistry, 2008
View PDFchevron_right
Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family
Dafydd Jones
Structure, 2010
View PDFchevron_right
Re-examination of the charge relay system in subtilisin comparison with other serine proteases
Jens Birktoft
Journal of Biological …, 1977
View PDFchevron_right
Molecular orbital analysis of the catalytic process of serine proteinases: Effect of environment on protonation of the histidine-aspartate diad of subtilisin
Paul Mezey
Journal of Molecular Structure-theochem, 1982
View PDFchevron_right
Computational Study of the Michaelis Complex Formation and the Effect on the Reaction Mechanism of Cruzain Cysteine Protease
Kemel Arafet
ACS Omega
View PDFchevron_right
Inhibition of subtilisin by substituted arylboronic acids
Manfred Philipp
FEBS Letters, 1981
View PDFchevron_right
Novel Protease Inhibitors via Computational Redesign of Subtilisin BPN′ Propeptide
Stefan Lutz
Biochemistry, 2012
View PDFchevron_right
Activity of Subtilisin Carlsberg in macromolecular crowding
Ajay Shaw
Journal of Photochemistry and Photobiology B: Biology, 2007
View PDFchevron_right
Subtilisin from Bacillus subtilis strain 72. The influence of substrate structure, temperature and pH on catalytic properties
Mikhail Gololobov
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1992
View PDFchevron_right
Folding Pathway Mediated by an Intramolecular Chaperone: Characterization of the Structural Changes in Pro-subtilisin E Coincident with Autoprocess ing
ujwal shinde
Journal of Molecular Biology, 1995
View PDFchevron_right
Probing structure-function relationships of serine hydrolases and proteases with carbamate and thiocarbamate inhibitors
Gialih Lin
The protein journal, 2006
View PDFchevron_right
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site
James Janc
Journal of Molecular Biology, 2001
View PDFchevron_right
The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-like Inhibitor A REFINED MECHANISM OF SERINE PROTEASE ACTION * □ S
Gergely Katona
View PDFchevron_right
Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations
Bill Hennen
Journal of the American Chemical Society, 1990
View PDFchevron_right