Erythrodermic follicular mucinosis (original) (raw)

1987, Clinical and Experimental Dermatology

AI-generated Abstract

The study presents a unique case of erythrodermic follicular mucinosis characterized by generalized symptoms, including erythema, alopecia, and severe skin involvement. This case revealed significant eosinophilia and an activated T cell population in the peripheral blood, highlighting a possibly neoplastic aspect of the disease. Treatment with oral steroids led to a positive response, suggesting steroid therapy may be beneficial for similar cases of widespread follicular mucinosis.

Follicular mucinosis associated with scarring alopecia, oligoclonal T-cell receptor V? expansion, and Staphylococcus aureus: When does follicular mucinosis become mycosis fungoides?

Journal of the American Academy of Dermatology, 1997

A diagnosis of alopecia mucinosa, occurring as a single scalp lesion, was made in a 40year-old white woman who had a history of trauma. Follicular mucinosis, Staphylococcus aureus, and oligoclonal expansion of the T-cell receptor vP chain genes 6 and 7 were present in the skin. Epidermotropic T-cell skin diseases with oligoclonal T-cell proliferations may be the result of HLA-and cytokine-determined reaction patterns to persistent antigens. (J Am Acad Dermatol 1997;36:828-31.) CASE REPORT A 40-year-old white woman had a 2-year history of a "bump on the scalp" at the site of trauma and suturing 30 years before. It enlarged gradually into a pruritic and crusted erythematous indurated plaque, with loss of hair Biopsy specimens had shown follicular mucinosis. Physical examination revealed a 2 x 3 cm, welldemarcated, indurated plaque, with a yellow crust on the middle posterior scalp (Fig. 1). A complete blood cell count and chemistry profile were normal. Cultures grew coagulase-positive Staphylococcus aureus and the patient was treated with oral dicloxacillin 1 gm daily with improvement. Several months later, the lesion was excised. The biopsy specimen showed marked scarring in the upper epidermis. Epidermal hyperkeratosis with effacement ORTHO This article is made possible through an educational grant from the Dermatological Division, Ortho Pharmaceutical Corporation. Supported in part by a fellowship sponsored by the Ladies Leukemia League of New Orleans, La. (C. M. J.), a physician's referral grant from M. D. Anderson Cancer Center (M. D.), the Burnell Chaney patient education fund to the patients at the MDACC CTCL clinic, and National Institutes of Health grant AR-39915.

Hair Bundles: A Presentation of Folliculitis

Australasian Journal of Dermatology, 1985

Case reports of three patients with folliculitis of the posterior scalp are presented. In each an abnormality of hair growth was observed in the affected area in which bundles of hairs emerged from each follicle. The individual hair shafts came from independent papillae but converged into a single infundibulum in the upper dermis, and there was an associated granulomatous inflammation. This type of compound follicle with staphylococcal infection has rarely been reported in man before. Some of the mechanisms by which compound follicles can be formed are discussed. FIGURE 1-Case 1, scalp. Pinkus H (1951): Multiple hairs (FlemingGiovannini). J Invest Derm 17:291. Mehregan AH, Thompson WS (1979): Pili multigemini; a report of a case in association with cleidocranial dysostosis. Brit J Derm 100:315. ' Weary PE, Hendricks AA, Wawner F, Ajgoanar G (1973): Pili bifurcati. Arch Derm 108:4. * Metz J, Metz G (1978): Naevoid hair bundles in man. Hautarzt 29586. Smith N (1978): Tufted folliculitis of the scalp. Proc Roy SOC Med 7 1 :606. Laymon CW, Murphy RJ (1947): The cicatricial alopecias. J Invest Derm 8:99.

Loading...

Loading Preview

Sorry, preview is currently unavailable. You can download the paper by clicking the button above.