Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw (original) (raw)

Additional Supporting Information may be found in the online version of this article. Authors' contributions: MV-R carried out mating, pharyngeal arches and skeletal dissections, designed experiments, performed statistical analysis, made figures and prepared the manuscript. SM carried out ISH and quantitative PCR experiments. EH carried out some ISH experiments. OB and SM maintained the animal colony, performed mouse mating and genotyping. GC provided medical expertise and scanners of FAS patients. HK provided Edn1 mutant mice and extensive discussion of the manuscript. GRM carried out ISH, analyzed Real Time PCR data and performed skeletal dissections. GRM and GL designed and coordinated the study, organized the results and prepared the manuscript. All authors read and approved the final manuscript.

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