original ) (raw )A monoclonal antibody recognizes a von Willebrand factor domain within the amino-terminal portion of the subunit that modulates the function of the glycoprotein IB- and IIB/IIIA-binding domains
Hans Deckmyn
Journal of Clinical Investigation, 1993
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Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding
Vicente Vicente
Journal of Biological Chemistry
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Purified A2 domain of von Willebrand factor binds to the active conformation of von Willebrand factor and blocks the interaction with platelet glycoprotein Ib
lucia morales
Journal of Thrombosis and Haemostasis, 2007
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Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal …
Elisabeth Hodson
Journal of Clinical …, 1985
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Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin. Role of platelet activation, fibrinogen, and two distinct membrane receptors
Mario Mazzucato
Journal of Clinical Investigation, 1987
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Platelet Aggregation Induced by a Monoclonal Antibody to the A1 Domain of von Willebrand Factor
hans deckmyn
Blood, 1998
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Shielding of the A1 Domain by the D'D3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein Ib-IX-V
Hans Deckmyn
Journal of Biological Chemistry, 2006
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Distinct Abnormalities in the Interaction of Purified Types IIA and 115 von Willebrand Factor with the Two Platelet Binding Sites , Glycoprotein Complexes
Mario Mazzucato
2013
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Factor VIII/von Willebrand protein. Modification of its carbohydrate causes reduced binding to platelets
KJ Kao
The Journal of biological chemistry, 1980
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von Willebrand factor (VWF) propeptide binding to VWF D′D3 domain attenuates platelet activation and adhesion
Kate Rittenhouse-Olson
Blood, 2012
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Regulation of von Willebrand Factor Binding to the Platelet Glycoprotein Ib-IX by a Membrane Skeleton-dependent Inside-out Signal
Richard Bodnar
Journal of Biological Chemistry, 2001
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Identification of Peptide Antagonists to Glycoprotein Ibα That Selectively Inhibit von Willebrand Factor Dependent Platelet Aggregation
Jaison Thomas
Biochemistry, 2008
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Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa
Mario Mazzucato
Journal of Clinical Investigation, 1990
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von Willebrand factor mediates platelet spreading through glycoprotein Ib and alphaIIbbeta3 in the presence of botrocetin and ristocetin, respectively
Laura Machesky
Journal of Thrombosis and Haemostasis, 2006
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Glycoprotein Ib-V-IX, a Receptor for von Willebrand Factor, Couples Physically and Functionally to the Fc Receptor γ-Chain, Fyn, and Lyn to Activate Human Platelets
Christine Edmead
Blood, 1999
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A critical role for 14-3-3ζ protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications
Richard Bodnar
Blood, 2005
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Glycoprotein Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor gamma-chain, Fyn, and Lyn to activate human platelets
Christine Edmead
Blood, 1999
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Destabilization of the A1 Domain in von Willebrand Factor Dissociates the A1A2A3 Tri-domain and Provokes Spontaneous Binding to Glycoprotein Ib and Platelet Activation under Shear Stress
Erik Sedlák
Journal of Biological Chemistry, 2010
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Promotion of binding of von Willebrand factor to platelet glycoprotein Ib by dimers of ristocetin
Hans Deckmyn
The Biochemical journal, 1995
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Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ib
Hans Deckmyn
Haematologica, 2013
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Phenotype changes resulting in high-affinity binding of von Willebrand factor to recombinant glycoprotein Ib-IX: analysis of the platelet-type von Willebrand disease mutations
Sasha Tait
Blood, 2001
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Crystal Structure of the von Willebrand Factor A1 Domain and Implications for the Binding of Platelet Glycoprotein Ib
Miguel Cruz
Journal of Biological Chemistry, 1998
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6 Von Willebrand factor and platelet function
Dominique Baruch
Baillière's Clinical Haematology, 1989
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Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers
Bahman Anvari
Blood, 2002
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Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF
Tadayuki Yago
Journal of Clinical Investigation, 2008
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Platelet receptors for human factor VIII/von Willebrand protein: functional correlation of receptor occupancy and ristocetin-induced platelet aggregation
KJ Kao
Proceedings of the …, 1979
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New Insights into von Willebrand Disease and Platelet Function
Hans Deckmyn
Seminars in Thrombosis and Hemostasis, 2012
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Interaction of von Willebrand factor with platelets and the vessel wall
grazia loredana mendolicchio
Hämostaseologie, 2015
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Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of alphaIIbbeta3 engagement
Dominique Baruch
Blood, 2003
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Filamin A binding to the cytoplasmic tail of glycoprotein Ib regulates von Willebrand factor-induced platelet activation
Julio c Resendiz
2003
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Platelet von Willebrand factor - structure, function and biological importance
Owen Smith
British Journal of Haematology, 2010
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Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction
Hendrik Feys
kuleuven-kulak.be
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The N-terminal Flanking Region of the A1 Domain Regulates the Force-dependent Binding of von Willebrand Factor to Platelet Glycoprotein Ib
Miguel Cruz
Journal of Biological Chemistry, 2013
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von Willebrand factor contained in a high purity FVIII concentrate (Fanhdi) binds to platelet glycoproteins and supports platelet adhesion to subendothelium under flow conditions
Vicente Vicente
Haematologica, 1999
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