Lack of Adherence to SHEA-IDSA Treatment Guidelines for Severe Clostridium difficile Infection is Associated with Increased Mortality (original) (raw)
Abstract
Background: Clostridium difficile infection (CDI) is associated with 14,000 deaths every year in the US according to the Center for Disease Control (CDC). In 2010, the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America (SHEA-IDSA) published guidelines stratifying the severity of CDI in patients based on their clinical presentation and laboratory values. They recommend specific initial treatment of CDI based on this severity stratification. Aim: 1) To determine our institution’s compliance with the Clostridium difficile treatment guidelines. 2) To determine whether noncompliance with the Clostridium difficile treatment guidelines was associated with adverse outcomes. Methods: Patients presenting to our institution from December 2012 to November 2013 with a diagnosis of CDI were identified. Clinical parameters, Laboratory values and Clinical course were obtained from electronic medical records. An adverse outcome of 90 day mortality with CDI ...
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