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Differential Modulation of Mitogen-activated Protein (MAP) Kinase/Extracellular Signal-related Kinase Kinase and MAP Kinase Activities by a Mutant Epidermal Growth Factor Receptor

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Journal of Biological Chemistry, 1995

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Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF

Lark Wong

2001

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Activation of the Ras/Mitogen-Activated Protein Kinase Pathway by Kinase-Defective Epidermal Growth Factor Receptors Results in Cell Survival but Not Proliferation

Normand Pouliot

1998

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The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors

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Pharmacology & Therapeutics, 2000

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Role of Tyrosine Kinase Receptors in Growth Factor Mediated Signal Transduction, with Specific Reference to MAPK/Rasand p13k-Akt Containing Pathways in Oncogenesis: A Qualitative Database Review

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Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation

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The epidermal growth factor receptor–tyrosine kinase: A promising therapeutic target in solid tumors

Carlos Arteaga

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V600EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

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Epidermal growth factor receptor (EGFR) signaling in cancer

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Association of epidermal growth factor receptor mutations with human papillomavirus 16/18 E6 oncoprotein expression in non-small cell lung cancer

Alper Toker

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Mutational Analysis of the EGF Receptor Proto-Oncogene

J. Schlessinger

Cell to Cell Signals in Mammalian Development, 1989

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Stimulation of Mitogenic Pathways through Kinase-Impaired Mutants of the Epidermal Growth Factor Receptor

Jonathan Ewald

Experimental Cell Research, 2001

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Epidermal Growth Factor Receptor Phosphorylation Sites Ser991 and Tyr998 Are Implicated in the Regulation of Receptor Endocytosis and Phosphorylations at Ser1039 and Thr1041

Myron Toews, Debra Romberger

Molecular & Cellular Proteomics, 2009

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Somatic mutations of the EGF receptor and their signal transducers affect the efficacy of EGF receptor-specific tyrosine kinase inhibitors

Noriko Gotoh

International journal of clinical and experimental pathology, 2011

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EGFR Signaling and its inhibition by EGFR inhibitors in NSCLC

Rajvi Patel

International Journal of Applied Sciences and Biotechnology, 2014

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EGFR Targeted Therapy: View from Biological Standpoint

Norman Sharpless

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Emerging functions of theEGFRin cancer

Letizia Lanzetti

Molecular Oncology, 2017

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The EGFR family: not so prototypical receptor tyrosine kinases

Mark Lemmon

2014

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EGFR and NF-κB: partners in cancer

Alain Chariot

Trends in Molecular Medicine, 2015

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Protein expression, gene amplification, epidermal growth factor receptor mutations and lung carcinoma

Zivka Eri

Vojnosanitetski pregled. Military-medical and pharmaceutical review, 2014

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Comparison and analysis Receptor Tyrosine Kinases associated EGFR gene and its variants

JASH MATHEW

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Identification of a human epidermal growth factor receptor-associated protein kinase as a new member of the mitogen-activated protein kinase/extracellular signal-regulated protein kinase family

Steven Pelech

Journal of Biological Chemistry, 1993

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Functional Analysis of Epidermal Growth Factor Receptor (EGFR) Mutations and Potential Implications for EGFR Targeted Therapy

Nikolas von Bubnoff

Clinical Cancer Research, 2009

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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

Fumin Chang, Rich Franklin

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2007

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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Bijay Jaiswal, Georgia Hatzivassiliou, Bonnie Liu, David Stokoe, Hartmut Koeppen, Kyung Song

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Alterations in Genes of the EGFR Signaling Pathway and Their Relationship to EGFR Tyrosine Kinase Inhibitor Sensitivity in Lung Cancer Cell Lines

Yang Xie

PLOS One, 2009

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Novel MEK1 Mutation Identified by Mutational Analysis of Epidermal Growth Factor Receptor Signaling Pathway Genes in Lung Adenocarcinoma

yan mardi

Cancer Research, 2008

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Epidermal growth factor receptor (EGFR), KRAS, and BRAF mutations in lung adenocarcinomas: A study from India

prerna guleria

Current Problems in Cancer, 2018

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Raf kinases in lung tumor development

Stefan Albert

Advances in Enzyme Regulation, 2003

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Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation

Ana Isabel Cosgaya

PLOS ONE, 2015

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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

Yaara Zwang

Oncogene, 2010

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Protein tyrosine kinase activities of the epidermal growth factor receptor and ErbB proteins: correlation of oncogenic activation with altered kinetics

Nandini Nair

Molecular and cellular biology, 1992

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