Complications of medically assisted conception in 3,500 cycles (original) (raw)
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Assisted Reproductive Technology: Techniques and Limitations
Journal of Bangladesh College of Physicians and Surgeons, 2010
Infertility is a source of social and psychological suffering for both men and women and can place great pressure on the relationship within the couple. One in six couples of any society remains infertile and 10% of them need help of assisted reproductive technology (ART). ART refers to all technology where gametes are manipulated outside the body. In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are the commonest of all type of ART. Bilateral tubal block, endometriosis, severe oligospermia, and azoospermia are the commonest indications for ART. Whoever is responsible for infertility women are usually treated for superovulation, which sometimes involves risk of the patient. Collection of oocyte is also invasive. Result of treatment in terms of pregnancy is not very satisfactory. Average pregnancy rate is 30%- 34% worldwide. Abortion and congenital anomaly rate is a bit higher than normal population, which is related to age of the female partner not related to...
The clinical benefit and safety of current and future assisted reproductive technology
Reproductive BioMedicine Online, 2012
Since the first birth by IVF was achieved in 1978, the techniques involved in assisted reproductive technology have grown at an enormous rate. However, new technology has rarely been robustly validated before clinical use and developing scientific understanding of the available techniques has done little to alter their use. Furthermore, there are inconsistencies in the available clinical studies and endpoints. The benefits of some technologies already established for routine use are currently dubious and there are clear ...
Fertility and Sterility, 2011
Objective: To analyze information on assisted reproductive technologies (ART) performed globally. Design: Data on access, efficacy, and safety of ART were collected for the year 2003 from 54 countries. Setting: National and regional ART registries globally. Patient(s): Patients undergoing ART globally. Intervention(s): Collection and analysis of international ART registry data. Main Outcome Measure(s): Number of cycles performed in reporting countries and regions globally for different ART procedures with resulting pregnancy, live birth and multiple birth rates. Result(s): A total of 433,427 initiated cycles reported in this registry resulted in 173,424 babies born. This corresponded to a delivery rate per aspiration of 22.4% for in vitro fertilization (IVF), 23.3% for intracytoplasmic sperm injection (ICSI), and a delivery rate per transfer of 17.1% for frozen embryo transfer. Although there is wide variation among countries and regions, the overall proportion of deliveries with twins and triplets from IVF and ICSI was 24.8% and 2.0%, respectively. There were wide variations in access, and compared with the previous report (year 2002), there was a 3.9% increase in the number of reported cycles and a minor increase in the delivery rate per aspiration. There was also a marginal decline in the mean number of embryos transfered and in the rate of multiple births. Conclusion(s): ART access, efficacy, and safety varies greatly globally. Collection and analysis of data over time will benefit ART patients, providers, and policy makers. (Fertil Steril Ò 2011;95:2209-22.
Effectiveness of Assisted Reproductive Technology
2008
Objectives:We reviewed the evidence regarding the outcomes of interventions used in ovulation induction, superovulation, and in vitro fertilization (IVF) for the treatment of infertility. Short-term outcomes included pregnancy, live birth, multiple gestation, and complications. Long-term outcomes included pregnancy and post-pregnancy complications for both mothers and infants.