The evaluation of chemotherapy and radiotherapy on thyroid gland in Sudanese cancer patients (original) (raw)
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An Analytical, Statistical Study of Thyroid Cancer Incidence in Sudan During 2005-2015
Global Journal of Public Health Medicine, 2019
Introduction: Sudan, the most diverse country in the African continent, is experiencing growing cancers problems. However, little is known about thyroid cancer epidemiology and patterns. the study aimed to analyse and describe the epidemiological characteristics and trends of thyroid cancer in, in the period1st January 2005 and 31st December 2015. Methods: This is retrospective population and hospital-based study. We analysed epidemiological data for digital medical records at both Radiation and Isotope Centre Khartoum (RICK), and Soba University Hospital, Khartoum, Sudan were reviewed. Results: In total, 1,062 cases were reported during 1st January 2005 and 31st December 2015. Of these, (360; 33.9%) were male and (702; 66.1%) were female. The highest number of cases was in the 25-54-year-old age group (451; 42.5%), and more than 65-year-old age (331; 31.2%). The most predominant type of thyroid cancer among the Sudanese population was Papillary carcinoma (734; 69.1%) followed by Fo...
Open Journal of Endocrine and Metabolic Diseases, 2016
Background and objective: Thyroid cancer is the most common endocrine malignancy. This report aims to describe the pattern of thyroid cancer presentations at King Abdulaziz University Hospital, Jeddah. Methods: This was a retrospect chart review of all thyroid cancer cases diagnosed between 2001 and 2010 at King Abdulaziz University Hospital, Jeddah. We documented patients' demographic and clinical data, including age at diagnosis, tumor type and size, extrathyroidal extension, and metastasis. Results: A total of 114 thyroid cancer cases were diagnosed from 2001 through 2010. Females comprise the majority of cases (female to male ratio of 4:1). The mean ages of patients diagnosed with different thyroid cancers were: papillary thyroid cancer, 39.6 years; follicular thyroid cancer, 43.2 years; medullary thyroid cancer, 55.8 years; and anaplastic thyroid cancer, 46.0 years. Papillary thyroid cancer was diagnosed in 88 cases (77%), follicular thyroid cancer in 19 cases (17%), medullary thyroid cancer in 5 cases (4%), and anaplastic thyroid cancer in 2 cases (2%). Conclusion: Thyroid cancers are more common among females. The disease is diagnosed at a relatively young age among our patients (40 years). Papillary thyroid cancer is the most common type of thyroid cancer.
A r c h i v e o f S I D Epidemiology of Thyroid Cancer in Jordan from 1996 to 2008
Middle East Journal of Cancer, 2011
Background: The incidence of thyroid cancer has varied from 2 per 100,000 in Europe to 21 per 100,000 in the Hawaiian Chinese population and is 2-3 fold more common in females. Middle East Cancer Consortium figures from 1996-2001 have recorded different age standardized incidence rates that ranged from 2 per 100,000 in Egypt to 7.5 per 100,000 among Israeli Jews. In Jordan the age standardized incidence rate of thyroid cancer was 3 per 100,000 during that period. This study aimed to define the incidence of thyroid cancer in Jordan and to explore the epidemiological characteristics of patients and tumors. Methods: This was a descriptive epidemiological study that utilized data reported to the Jordan Cancer Registry during 1996-2008. Results: The incidence rate in Jordan varied during the period from 1996 to 2008; however the recorded rate (2.6 per 100,000) in 1996 and 2008 was similar. The incidence rate was higher among Jordanian females. Age specific incidence rate and age standardized incidence rate were parallel during the study period with no peaks. The most common morphological type of thyroid cancer in Jordan was papillary carcinoma (76%). The average annual incidence during the study period was highest (3.3 per 100,000) in Amman and (2.2 per 100,000) in Jarash governorates. Conclusion: The results of our study are consistent with international studies. The incidence of thyroid cancer in Jordan is not high when compared with other countries. The high incidence of thyroid cancer in Amman and Jarash governorates in comparison to the incidence in other governorates needs further assessment.
Risk factors of thyroid cancer in Babol, Northern Iran
Caspian Journal of Internal Medicine, 2011
Background: Thyroid cancer is the most common endocrine malignancy. Several risk factors were found to play a role in thyroid cancer. The purpose of the study was to determine the risk factors for thyroid cancer, in Babol, north of Iran. Method: 80 patients with thyroid cancer were selected as case group and 160 people living in the neighborhood of the patients as control group. Risk factors in both groups were collected and compared. The odds ratio (OR) as well as the marginal logistic regression model were used to estimate the possible risk factors. Result: X-ray exposure, radioactive exposure, family history of thyroid cancer, history of hyperthyroidism, hypothyroidism and thyroid resection were found to be the risk factors of thyroid cancer (p<0.05). Passion exposure, OCP user, history of hysterectomy, history of thyroid nodule were not correlated to thyroid cancer (p>0.05). Conclusion: History of goiter or other benign thyroid diseases are among the thyroid cancer risk factors in some community-based interventions to prevent or treat the disease in early stages are recommended in our region.
Risk factors of differentiated thyroid cancer in Sohag, Egypt
International Journal of Current Research in Medical Sciences, 2016
Introduction: Two folds increase in differentiated thyroid cancer (DTC) have been noticed in the past few decades. This might be linked to either increase in the exposure of individuals to environmental risk factors or improved diagnostic techniques or both of them. We aimed at studying risk factors of thyroid cancer in Sohag, Egypt. Methodology: retrospective case control study that was conducted in Oncology & Nuclear department of Sohag University Hospital in four months duration from July 2016 to October 2016.105 DTC cases were compared to 150 controls for presence of these risk factors (radiation, radioactive iodine, obesity, family history of thyroid cancer, previous thyroid nodule and smoking). Results: out of 105 DTC cases, 94.1% were females, 60.2% had papillary carcinoma. Compared to controls, obesity and positive history of thyroid nodule were found to be very high significant risk factors (P value <0.001), residence also showed significant difference between cases and control (P value <0.05). While no significant difference was found as regard smoking and positive family history of thyroid cancer. Conclusion: Ultra sonographic finding should be the corner stone in management of thyroid nodule in any patient whatever the age and increase awareness about hazards of obesity are needed especially among uneducated rural females.
Incidence rate of thyroid cancer in Iranian population, trend analysis from 2003 to 2009
International journal of epidemiologic research, 2015
Background and aims: Thyroid cancer is the most common endocrine malignant and papillary cancer and three times more prevalent in women than men. The aim of this study was to evaluate the incidence rate and trend of thyroid cancer in Iranian population. Methods: National incidence was rated by Iran National Cancer Registry data derived from Iran's annual national cancer registration reported from 2003 to 2009. The crude rate and age standardized rate were used to express the incidence of thyroid cancer. Results: The results indicated that, the incidence of thyroid cancer increased from 2003 to 2009. The age standardized rate for women and men increased from 2.02 and 0.82 to 4.2 and 1.36 per 100,000, respectively. Conclusion: This study indicated remarkable increasing trends in thyroid cancer incidence. So, attention to high risk groups and public programs is necessary to reduce the incidence of this cancer in future.
Epidemiology of Thyroid Cancer in Jordan from 1996 to 2008
Middle East Journal of Cancer, 2011
Background: The incidence of thyroid cancer has varied from 2 per 100,000 in Europe to 21 per 100,000 in the Hawaiian Chinese population and is 2-3 fold more common in females. Middle East Cancer Consortium figures from 1996-2001 have recorded different age standardized incidence rates that ranged from 2 per 100,000 in Egypt to 7.5 per 100,000 among Israeli Jews. In Jordan the age standardized incidence rate of thyroid cancer was 3 per 100,000 during that period. This study aimed to define the incidence of thyroid cancer in Jordan and to explore the epidemiological characteristics of patients and tumors. Methods: This was a descriptive epidemiological study that utilized data reported to the Jordan Cancer Registry during 1996-2008. Results: The incidence rate in Jordan varied during the period from 1996 to 2008; however the recorded rate (2.6 per 100,000) in 1996 and 2008 was similar. The incidence rate was higher among Jordanian females. Age specific incidence rate and age standardized incidence rate were parallel during the study period with no peaks. The most common morphological type of thyroid cancer in Jordan was papillary carcinoma (76%). The average annual incidence during the study period was highest (3.3 per 100,000) in Amman and (2.2 per 100,000) in Jarash governorates. Conclusion: The results of our study are consistent with international studies. The incidence of thyroid cancer in Jordan is not high when compared with other countries. The high incidence of thyroid cancer in Amman and Jarash governorates in comparison to the incidence in other governorates needs further assessment.
2020
Background: Thyroid cancer is the most common malignant disease of endocrine system and its incidence is rapidly increasing globally (about three to four times higher among females and accounts the sixth most common malignancy diagnosed in women). Among the four major types of thyroid cancer, papillary thyroid cancer (PTC) accounts 85-90% from all thyroid cases, followed by follicular thyroid cancer (FTC) which accounts for 5-10% of cases.Materials and Methods: A retrospective data of 260 patients who underwent thyroid surgery from 2015 to 2019 were included in the study and the status of the disease (clinical manifestations, laboratory/pathology findings (thyroid function tests (TFTs) and biopsy) were reviewed from patient cards. The pattern of thyroid cancer was discriminated based on histo-pathological biopsy result. Descriptive and analytical statistics were applied to express the finding and reported by tables, figures and narration. Cross tabulation and logistic regression was...