New Cd(II), Mn(II) and Ag(I) Schiff Base Complexes : Synthesis, Characterization, DNA Binding and Antimicrobial Activity (original) (raw)

Some Cd (II), Mn (II) and Ag (I) complexes derived from Schiff base ligand, obtained by the condensation of 4-Nitrobenzaldehyde and 2-amino-3-hydroxypyridine were synthesized. The complexes were characterized by elemental analysis, molar conductivity, magnetic susceptibility, IR, UV-Vis spectral data and thermal analysis. The complexes were found to be non-electrolytic in nature depending on value of molar conductance. From the spectral data, an octahedral geometry has been approached for all the complexes except Ag (I) complex which is tetrahedral. Moreover, the metal complexes have been tested for their antibacterial and antifungal activity. Furthermore, DNA interaction of these complexes was tempted by using Electronic spectra, viscosity measurements and gel electrophoresis. The experimental results indicated that the investigated complexes could associate with DNA via intercalative mode and showed a different DNA binding activity.