Detection of susceptibility loci by genome-wide linkage analysis (original) (raw)

Identifying susceptibility genes using linkage and linkage disequilibrium analysis in large pedigrees

Maha Karnoub

Genetic Epidemiology

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Association Mapping of Disease Loci, by Use of a Pooled DNA Genomic Screen

Anne Bowcock

The American Journal of Human Genetics, 1997

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The Power to Detect Linkage in Complex Disease by Means of Simple LOD-Score Analyses

David A Greenberg

The American Journal of Human Genetics, 1998

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Linkage disequilibrium maps constructed with common SNPs are useful for first-pass disease association screens

Amy Drendel

Genomics, 2004

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Design and Analysis of Genetic Association Studies to Finely Map a Locus Identified by Linkage Analysis: Sample Size and Power Calculations

Leslie Baier

Annals of Human Genetics, 2008

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Linkage Analysis of a Complex Disease through Use of Admixed Populations

Robert Elston

American Journal of Human Genetics, 2004

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On the analysis of sequence data: testing for disease susceptibility loci using patterns of linkage disequilibrium

Wai-ki Yip

Genetic Epidemiology, 2011

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Optimal Ascertainment Strategies to Detect Linkage to Common Disease Alleles. Authors' Reply

Elliot Gershon

The American Journal of Human Genetics, 1999

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Comparison of family-based association tests in chromosome regions selected by linkage-based confidence intervals

Shelley Bull

BMC Genetics, 2005

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Linkage analysis of complex diseases using microsatellites and single-nucleotide polymorphisms: application to alcoholism

Jérémie Nsengimana

BMC Genetics, 2005

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GLOSSI: a method to assess the association of genetic loci-sets with complex diseases

Jean-pierre Kocher, Hugues Sicotte

BMC Bioinformatics, 2009

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Linkage Disequilibrium and the Mapping of Human Disease Genes

nahid askari

International Journal of Genetics and Genomics, 2014

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A comparison of sib-pair linkage tests for disease susceptibility loci

Robert Elston

Genetic Epidemiology, 1985

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The Value of Molecular Haplotypes in a Family-Based Linkage Study

A. Sorant

The American Journal of Human Genetics, 2006

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True and False Positive Peaks in Genomewide Scans: Applications of Length-Biased Sampling to Linkage Mapping

Joe Terwilliger

The American Journal of Human Genetics, 1997

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Genome-wide Linkage Analysis with Clustered SNP Markers

Ole Olstad

Journal of Biomolecular Screening, 2008

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Allelic association with SNPs: metrics, populations, and the linkage disequilibrium map

Pui-yan Kwok

Human Mutation, 2001

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Optimal Ascertainment Strategies to Detect Linkage to Common Disease Alleles

Elliot Gershon

The American Journal of Human Genetics, 1998

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Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes

Volodymyr Dvornyk

BMC Genetics, 2004

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Using parametric multipoint lods and mods for linkage analysis requires a shift in statistical thinking

Lisa Strug

Human heredity, 2011

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Using Linkage Analysis to Detect Gene-Gene Interaction by Stratifying Family Data on Known Disease, or Disease-Associated, Alleles

Barbara Corso

PLoS ONE, 2014

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Selection of SNP subsets for association studies in candidate genes: comparison of the power of different strategies to detect single disease susceptibility locus effects

Emmanuelle Génin

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Comparison of Six Statistics of Genetic Association Regarding Their Ability to Discriminate between Causal Variants and Genetically Linked Markers

A GP

Human Heredity, 2011

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False-positive rates in two-point parametric linkage analysis

Claire Simpson, C. Cropp

BMC Proceedings, 2014

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Models and Tests of Linkage and Association Studies of Quantitative Trait Locus for Multi-Allele Marker Loci

Joanna Floros

Human Heredity, 2002

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On the use of haplotype phylogeny to detect disease susceptibility loci

Jean-pierre Hugot, Emmanuelle Génin

BMC genetics, 2005

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Fine-scale linkage disequilibrium mapping: a comparison of coalescent-based and haplotype-clustering-based methods

Sungho Won

BMC Proceedings, 2007

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Factors affecting statistical power in the detection of genetic association

Derek Gordon

Journal of Clinical Investigation, 2005

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Direct Power Comparisons between Simple LOD Scores and NPL Scores for Linkage Analysis in Complex Diseases

David A Greenberg

The American Journal of Human Genetics, 1999

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Identification of susceptibility loci contributing to a complex disease using conventional segregation, linkage, and association methods

Neil Lamb

Genetic Epidemiology, 1995

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A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci

Joe Terwilliger

American journal of human genetics, 1995

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Linkage Analysis in the Presence of Errors III: Marker Loci and Their Map as Nuisance Parameters

Joe Terwilliger

The American Journal of Human Genetics, 2000

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Simultaneous localization of two linked disease susceptibility genes

Shelley Bull

Genetic Epidemiology, 2005

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Linkage analysis of the simulated data – evaluations and comparisons of methods

Mark Irwin

BMC Genetics, 2003

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Linkage Analysis in the Next-Generation Sequencing Era

Joan Bailey-Wilson

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