Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation (original) (raw)

Function Critical for Thymic Epithelial Controls the Expression of Genes The Autoimmune Regulator Directly

Kenneth Tung

2010

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Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells

Claude Perreault

Journal of immunology (Baltimore, Md. : 1950), 2015

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The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function

Sharad Purohit

The Journal of Immunology, 2007

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Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire)

Nicole Pezzi

Immunobiology, 2013

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Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells

Christoph Cremer

Proceedings of the National Academy of Sciences, 2010

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Models of Aire-Dependent Gene Regulation for Thymic Negative Selection

J. Dooley

Frontiers in Immunology, 2011

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Aire Controls in Trans the Production of Medullary Thymic Epithelial Cells Expressing Ly-6C/Ly-6G

Haruo Kozono

The Journal of Immunology

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Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

Sunitha Kogenaru

Journal of Experimental Medicine, 2005

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Reduced Thymic Aire Expression and Abnormal NF- B2 Signaling in a Model of Systemic Autoimmunity

Maree Hammett, Richard Boyd

The Journal of Immunology, 2009

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Gene Dosage-limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity

Daniel GRAY

Journal of Experimental Medicine, 2004

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Faculty of 1000 evaluation for Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity

Andrea Sant

F1000 - Post-publication peer review of the biomedical literature, 2004

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An Organized Medullary Epithelial Structure in the Normal Thymus Expresses Molecules of Respiratory Epithelium and Resembles the Epithelial Thymic Rudiment of Nude Mice

J. Dooley

The Journal of Immunology, 2005

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Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells

Eduardo Donadi

Frontiers in immunology, 2016

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Alterations of the Medullary Epithelial Compartment in the Aire-Deficient Thymus: Implications for Programs of Thymic Epithelial Differentiation

J. Dooley

The Journal of Immunology, 2008

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Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

Georg Holländer

Immunity, 2008

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RANK signals from CD4+3 inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

Hamish Scott

Journal of Experimental Medicine, 2007

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Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes

Geraldo Passos

Frontiers in immunology, 2018

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The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids

Ana Carolina Cassiano

2021

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Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

Georg Holländer

Genome Research, 2014

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Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

Kim Staats

European Journal of Immunology, 2013

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Aire-expressing thymic medullary epithelial cells originate from 5t-expressing progenitor cells

Georg Holländer

Proceedings of the National Academy of Sciences, 2013

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The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells

Tamara Lowen

The Journal of Immunology, 2008

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Editorial: The Role of Aire, microRNAs and Cell–Cell Interactions on Thymic Architecture and Induction of Tolerance

Geraldo Passos

Frontiers in Immunology, 2015

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A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery

Hamish Scott

The Journal of Immunology, 2008

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Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin

Hamish Scott

Nature Immunology, 2007

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Aire and T cell development

Maureen Su

Current Opinion in Immunology, 2011

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Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development

Georg Holländer

Frontiers in Immunology

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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

Daniel GRAY

Journal of Experimental Medicine, 2007

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