A class switch control region at the 3′ end of the immunoglobulin heavy chain locus (original) (raw)

Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions

Ahmed Khamlichi

Proceedings of the National Academy of Sciences, 2010

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Towards a comprehensive view of immunoglobulin class switching

Clifford Snapper

Immunology Today, 1993

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Class Switching in B Cells Lacking 3 9 Immunoglobulin Heavy Chain Enhancers

Roger Ferrini

1998

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Immunoglobulin class switching appears to be regulated by B-cell antigen receptor-specific T-cell action

Michael Zemlin

European Journal of Immunology, 2012

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Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching

Janet Stavnezer

The EMBO Journal, 1986

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Lymphocytes Downstream Switch Regions in B Between Ig Heavy Chain-µ and Generation of Switch Hybrid DNA

Kenneth Marcu, Diane Henry

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Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

Werner Müller

Proceedings of the National Academy of Sciences, 1986

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Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation

Kai-michael Toellner

Journal of Experimental Medicine, 1996

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Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells

Daniel Budman

Journal of Clinical Investigation, 1996

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Evidence for class-specific factors in immunoglobulin isotype switching

Janet Stavnezer

The Journal of …, 2000

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Categorical selection of the antibody repertoire in splenic B cells

Michael Zemlin

European Journal of Immunology, 2007

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Lang RB, Stanton LW, and Marcu KB. On immunoglobulin heavy chain switching: Two 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed. Nucl Acids Res 10:611-630

Kenneth Marcu, Lawrence Stanton

Nucleic Acids Research

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes

Janet Stavnezer

Journal of Experimental Medicine, 1985

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Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells

Michel Cogné

The Journal of Immunology, 2005

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IgG subclass switch capacity is low in switched and in IgM-only, but high in IgD+IgM+, post-germinal center (CD27+) human B cells

Vincent Kindler

European Journal of Immunology, 2001

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Antibody class switching differs among SJL, C57BL/6 and 129 mice

Janet Stavnezer

International Immunology, 2007

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Comparison of immunoglobulin heavy chain isotype expression in peyer's patch and splenic B-cells

Gayle Woloschak

Molecular Immunology, 1986

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Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity

rami hershkoviz

Proceedings of the National Academy of Sciences, 2002

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Cell surface immunoglobulin. XVIII. Functional differences of B lymphocytes bearing different surface immunoglobulin isotypes

jack kettman

Journal of Experimental Medicine, 1976

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Regulation of B-lymphocyte activation, proliferation, and immunoglobulin secretion

Peter Hornbeck

Cellular Immunology, 1986

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Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production

Paul C M van den Berk

Proceedings of the National Academy of Sciences, 2011

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Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

John Kearney

International Immunology, 1997

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Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

Rusty Lansford

Genes & Development, 1994

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Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development

Eric Meffre

Journal of Clinical Investigation, 2001

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B Cell Receptor-independent Stimuli Trigger Immunoglobulin (Ig) Class Switch Recombination and Production of IgG Autoantibodies by Anergic Self-Reactive B Cells

Giang Phan

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T CELL-DERIVED B CELL DIFFERENTIATION FACTOR(S) Effect on the Isotype Switch of Murine B Cells

Ellen Vitetta

2000

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B lymphocytes may escape tolerance by revising their antigen receptors

Marko Radic

Journal of Experimental Medicine, 1993

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Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination

Klaus Rajewsky

Journal of Experimental Medicine, 2011

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Differential sensitivity of B lymphocyte populations to IgM receptor ligation is determined by local factors

Jan Andersson

International Immunology, 1997

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Regulation of B-Lymphocyte Activation, Proliferation, and Differentiation

Peter Hornbeck, Clifford Snapper

Annals of the New York Academy of Sciences, 1987

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Induction of Ig Somatic Hypermutation and Class Switching in a Human Monoclonal IgM+ IgD+ B Cell Line In Vitro: Definition of the Requirements and Modalities of Hypermutation

Hong Zan

The Journal of Immunology

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Enhanced IgA Class Switching in Marginal Zone and B1 B Cells Relative to Follicular/B2 B Cells

Janet Stavnezer

The Journal of Immunology, 2006

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Ig-α Cytoplasmic Truncation Renders Immature B Cells More Sensitive to Antigen Contact

Klaus Rajewsky

Immunity, 1999

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