Phytochemistry and Pharmacological Properties of Ginger (Zingiber officinale) (original) (raw)

Abstract

Zingiber officinale is a plant native to India, which has been largely employed as flavoring agent in flavorful dishes such as curries and sweets such as cakes and biscuits, alcoholic beverages. Ginger is a well known herbal medicine, which is usually used in traditional medicine in all over the world. Many pharmacological activities of ginger are antiemetic, antidiabetic, analgesic, antiarthritic, anticancer, antioxidant, antiulcer, antimicrobial, anti-inflammatory immunomodulatory and cardiovascular activities. The pungency of the ginger is due to gingerols and shogaols. The main components of ginger are the aromatic essential oils, antioxidants and the pungent oleo-resin. These aromatic or pungent compounds have been identified as the phenylalkylketones, known as gingerols, shogaols, and zingerone.

Loading...

Loading Preview

Sorry, preview is currently unavailable. You can download the paper by clicking the button above.

References (37)

  1. Agrawal, M., Walia, S., Dhingra, S. and Khambay, B.P.S. (2001). Insect growth inhibition antifeedant and antifungal activity of compounds isolated derived from Zingiber officinale Roscoe, ginger rhizome. Pest Manag Sci., 57:289-300.
  2. Ahmed, R.S., Steh, V. and Banerjee, B.D. (2000). Influence of dietary ginger (Zingiber officinales Roscoe) on antioxidant defense system in rat, comparison with ascorbic acid. Indian J. Exp. Biol., 38:604-606.
  3. Al-Amin, Z. M., Thomson, M., Al-Qattan, K. K., Peltonen-Shalaby, R. and Ali, M. (2006). Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. British Journal of Nutrition, 96(4):660-6.
  4. Akhani, S. P., Vishwakarma, S. L. and Goyal, R. K (2004). Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol., 56: 101 -105.
  5. Ali, B. H., Blunden, G., Tanira, M. O. and Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol., 46: 409-420.
  6. Baliga, M.S., Haniadka, R., Pereira, M.M., Thilakchand, K. R., Rao, S. and Arora, R. (2012). Radioprotective effects of Zingiber officinale roscoe (ginger): Past, present and future. Food & function, 3(7): 714-723.
  7. Baliga, M.S., Latheef, L., Haniadka, R., Fazal, F., Chacko, J. and Arora, R. (2013). Ginger (Zingiber officinale Roscoe) in the treatment and prevention of Arthritis. Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases. pp. 529-544.
  8. Bartley, J. and Jacobs, A. (2000). Effects of drying on flavor compounds in Australian- grown ginger (Zingiber officinale). Journal of the Science of Food and Agriculture, 80: 209-215.
  9. Behera, B. and Yadav, D. (2013). Current Researches on Plants Having Antidiabetic Potential-An Overview. Research and Reviews: Journal of Botanical Sciences, 2(2): 4-17.
  10. Bellik, Y. (2014). Total antioxidant activity and antimi-crobial potency of the essential oil and oleo-resin of Zingiber officinale Roscoe. Asian Pac. J. Trop. Dis., 4: 40-44.
  11. Phytochemistry and........Ginger (Zingiber officinale) Wakchaure and Ganguly 2018
  12. Chrubasik, S., Pittler, M.H. and Roufogalis, B.D. (2005). Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine, 12:684-701.
  13. Dev, P., Katiyar, N.S., Singh, A.P. and Gangwar, A.K. (2016). Evaluation of anti- arthritic potential of zingiber officinale in experimental rats European Journal of Pharmaceutical and Medical Research, 3(4), 305-308.
  14. El-Abhar, H.S., Hammad, L.N. and Gawad, H.S. (2008). Modulating effect of ginger extract on rats with ulcerative colitis. Journal of Ethnopharmacology, 118(3): 367-372.
  15. Ernst, E. and Pittler, M.H. (2006). Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials" (PDF). British Journal of Anesthesia, 84(3): 367-371.
  16. Famurewa, A.V., Emuekele, P.O. and Jaiyeoba, K.F. (2011). Effect of Drying and Size Reduction on the Chemical and Volatile Oil Contents of Ginger (Zingiber officinale). Journal of Medicinal Plants Research, 14: 2941-2944.
  17. Ghayur, M.N. and Gilani, A.H. (2005). Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders. Dig. Dis. Sci., 50(10):1889-1897.
  18. Gupta, S. K. and Sharma, A. (2014). Medicinal properties of Zingiber officinale Roscoe- A Review. Journal of Pharmacy and Biological Sciences, 9(5): 124-129.
  19. Jagetia, G. C., Baliga, M.S., Venkatesh, P. and Ulloor, J. N. (2003). Influence of ginger rhizome (Zingiber officinale Rosc.) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat. Res., 160: 584-592.
  20. Kadnur, S. V and Goyal, R. K. (2005). Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats. Indian J. Exp. Biol., 43:1161-4.
  21. Kemper, K. J. (1999). Ginger (Zingiber offici-nale).Longwood Herbal Task Force, 3:1-18.
  22. Khaki, A., Fathiazad, F., Nouri, M., Khaki, A. A., Chelar, C., Ozanci, C., Ghafari- Novin M. and Hamadeh, M. (2009). The effects of ginger on spermatogenesis and sperm parameters of rat. Iranian J. Reprod. Med., 7:7-12.
  23. Kim, E.C., Min, J.K., Kim, T.Y., Lee, S. J., Yang, H.O., Han, S., Kim, Y.M. and Kwon, Y.G. (2005). Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo. Biochemical and Biophysical Research Communications, 335: 300-308.
  24. Meena, M. R. (1992). Studies on antimicrobial activity of various spices and their oils. M.Sc. Thesis: Indian Agricultural Research Institute, New Delhi.
  25. Mowrey, D. B. and Clayson, D. E. (1982). Motion sickness, ginger and psychophysics. Lancet I: 6557.
  26. Nanjundaiah, S.M., Annaiah, H.N.M and Shylaja M.D. (2011). Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-Oxidative Mol. Biol. and Pharm. of Beneficial Plants ISBN 978-93-85995-56-9
  27. Phytochemistry and........Ginger (Zingiber officinale) Wakchaure and Ganguly 2018
  28. Mechanism. Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine, 1 (1):1-13.
  29. Nya, E.J. and Austin, B. (2009). Use of dietary ginger, Zingiber officinale Roscoe as an immunostimulant to control Aeromonas hydrophila infections in rainbow trout, Oncorhynchus mykiss (walbaum). Journal of Fish Diseases, 32: 971-977.
  30. Nweze, E.I., Okafor, J.I. and Njoku, O. (2004). Antimicrobial Activities of Methanolic extracts of Trema guineesis (Schumm and Thorn) and Morinda lucida Benth used in Nigerian Herbal Medicinal Practice. Journal of Biological Research and Biotechnology, 2(1): 39-46.
  31. Platel, K. and Srinivasan, K. (2000). Influence of dietary spices and their active principles on pancreatic digestive enzymes in albino rats. Nahrung, 1: 42-46.
  32. Nanjundaiah, S. M., Annaiah, H. N. M and Shylaja M. D. (2011). Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-Oxidative Mechanism. Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine, 1 (1):1-13.
  33. Sontakke, S., Thawani, V. and Naik, M.S. (2003). Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: a randomized, cross-over, double blind study. Indian Journal of Pharmacology, 35: 32-36.
  34. Srinivasan, K. and Sambaiah, K. (1991). The effect of spices on cholesterol 7-alpha hydroxylase activity and on serum and hepatic cholesterol levels in the rat". International Journal of Vitamins and Nutrition Research, 61(4):364-369.
  35. Thomson, M., Al-Qattan, K.K., Al-Sawan, S. M., Alnaqeeb, M.A., Khan I. and Ali, M. (2002). The use of ginger (Zingiber officinale Rosc.) as a potential anti- inflammatory and antithrombotic agent. Prostaglandins, Leukotrienes and Essential Fatty Acids, 67 (6): 475-478.
  36. Wohlmuth, H., Leach, D. N., Smith, M. K. and Myers, S.P. (2005). Gingerol Content of Diploid and Tetraploid Clones of Ginger (Zingiber officinale Roscoe). Journal of Agricultural and Food Chemistry., 53: 5772-5778. http://dx.doi.org/10.1080/10408398209527343.
  37. Zick, S. M., Djuric, Z., Ruffin, M, T., Litzinger, A. J., Normolle, D.P., Alrawi, S., Feng, M. R. and Brenner, D. E. (2008). Pharmacokinetics of 6-gingerol, 8- gingerol, 10-gingerol, and 6-shogaol and conjugate me-tabolites in healthy human subjects. Cancer Epidemiol Biomarkers Prev., 17: 1930-1936.