Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome (original) (raw)

Features of complement activation-related pseudoallergy to liposomes with different surface charge and PEGylation: Comparison of the porcine and rat responses

Janos Szebeni

Journal of Controlled Release, 2014

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Liposome-induced pulmonary hypertension: properties and mechanism of a complement-mediated pseudoallergic reaction

Lajos Baranyi

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Hemodynamic Changes Induced by Liposomes and Liposome-Encapsulated Hemoglobin in Pigs A Model for Pseudoallergic Cardiopulmonary Reactions to Liposomes: Role of Complement and Inhibition by Soluble CR1 and AntiC5a Antibody

Janos Szebeni

2000

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Acute physiological changes caused by complement activators and amphotericin B-containing liposomes in mice

László Dézsi

International Journal of Nanomedicine

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Complement Activation-Related Cardiac Anaphylaxis in Pigs: Role of C5a Anaphylatoxin and Adenosine in Liposome-Induced Abnormalities in ECG and Heart Function

Lajos Baranyi

2005

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Surprising lack of liposome-induced complement activation by artificial 1,3-diamidophospholipids in vitro

Janos Szebeni

Nanomedicine: Nanotechnology, Biology and Medicine, 2015

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Animal Models of Complement-Mediated Hypersensitivity Reactions to Liposomes and Other Lipid-Based Nanoparticles

Janos Szebeni

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Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: Prediction and prevention

Janos Szebeni

Advanced Drug Delivery Reviews, 2011

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Cardiopulmonary and hemodynamic changes in complement activation-related pseudoallergy

Laszlo Rosivall, László Dézsi, Rudolf Urbanics

Health, 2013

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Complement Activation-Related Pathophysiological Changes in Anesthetized Rats: Activator-Dependent Variations of Symptoms and Mediators of Pseudoallergy

Janos Szebeni

Molecules, 2019

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Complement Activation - Related Hypersensitivity Reactions Caused by Pegylated Liposomes Search for an Alternative Long-Circulating Liposome Formulation Without Complement Activation

Lajos Baranyi

2003

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Cerebrovascular Involvement in Liposome—Induced Cardiopulmonary Distress in Pigs

Michael Bodo

Journal of Liposome Research, 2005

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Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil(R)): possible role in hypersensitivity reactions

Janos Szebeni

Annals of Oncology, 2003

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Complement Activation-Related Pseudoallergy Caused by Liposomes, Micellar Carriers of Intravenous Drugs, and Radiocontrast Agents

Rudolf Urbanics

Critical Reviews™ in Therapeutic Drug Carrier Systems, 2001

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Rodent models of complement activation-related pseudoallergy: Inducers, symptoms, inhibitors and reaction mechanisms

Janos Szebeni

European Journal of Nanomedicine, 2015

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The complement system enhances the clearance of phosphatidylserine (PS)-liposomes in rat and guinea pig

tran huong

International Journal of Pharmaceutics, 2001

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Szebeni_Nanomedicine_2012.pdf

Janos Szebeni

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Complement activation by PEGylated liposomes containing prednisolone

Reka Nemes

European Journal of Pharmaceutical Sciences, 2013

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Potentiation of liposome-induced complement activation by surface-bound albumin

Lajos Baranyi

Biochimica Et Biophysica Acta-biomembranes, 2002

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