Application of Gene Therapy towards Treatment of Cancer: Potentials and Future Developments (original) (raw)
Gene therapy is an exciting new field of personalized medicine, allowing for medical procedures that can target disease Cancer which is significant health burden, especially in developed countries, and the most lethal diseases that affect the major population in the world . Thus, a more selective method of targeting tumor cells is needed. In particular, gene therapy holds great potential to selectively target cancer cells, to destroy it .Technologies that involve gene transfer treatments allow for the insertion of foreign DNA into tumour cells, resulting in restored protein expression or altered function. Gene therapy can also be used as a form of immunotherapy, Cancer gene therapy using Mesenchymal stem cells, Nanotechnology for Cancer Treatment Additionally, oncolytic virotherapy uses classes of genetically modified viruses that can specifically target and interfere with tumour cells. The ongoing development of the CRISPR/Cas9 gene editing tool may also have promise in future therapeutic applications, with the tool being capable of removing cancer-causing. There are still many questions of safety, efficacy, and commercial viability which remain to be resolved with many gene therapy procedures. There is also emerging controversy over the ethical, legal, and moral implications that modifying the genetic content of human beings will have on society.
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