Isolation and partial characterization of actinomycetes with antimicrobial activity against multidrug resistant bacteria (original) (raw)

2012, Asian Pacific Journal of Tropical Biomedicine

AI-generated Abstract

Isolation and partial characterization of actinomycetes with antimicrobial activity against multidrug resistant bacteria Actinobacteria are a dominant bacterial phylum found in natural substrates, known for their role in the carbon cycle and as a significant source of antibiotics. This study aimed to isolate actinomycete strains from diverse habitats in Gwalior and evaluate their antimicrobial activity against multidrug resistant pathogens, particularly Methicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Resistant Enterococci (VRE), and Escherichia coli. Seven strains were isolated and characterized biochemically, with MITS 1005 demonstrating the highest antibacterial activity. The findings highlight Gwalior's rich actinobacterial biodiversity and its potential contributions to the pharmaceutical industry.