Efficacy of dietary hempseed oil in patients with atopic dermatitis (original) (raw)
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International Journal of Molecular Sciences, 2020
Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays desirable components of oils with special dietary and functional properties. Their therapeutic and health-promoting effects have already been established in various chronic inflammatory and autoimmune diseases through various mechanisms, including modifications in cell membrane lipid composition, gene expression, cellular metabolism, and signal transduction. The application of ω-3 and ω-6 PUFAs in most common skin diseases has been examined in numerous studies, but their results and conclusions were mostly opposing and inconclusive. It seems that combined ω-6, gamma-linolenic acid (GLA), and ω-3 long-chain PUFAs supplementation exhibits the highest potential in diminishing inflammatory processes, which could be beneficial for the management of inflammatory skin diseases, such as atopic dermatitis, psoriasis, and acne. Due to significant population and individually-based genetic variations that impact PU...
Assessing Olive, Palm Kernel, and Groundnut Oils for their Dermatologically-Active Agents
International Journal of Scientific Research in Science and Technology, 2019
Skin is the largest organ in the human body and plays important role and hence various expensive creams are formulated to care for it. People place much premium in using expensive creams with little or no knowledge of what less expensive creams (olive, palm kernel, and groundnut oils) can offer in respect of skin care. The aim of this research work was to assess and compare the levels of skin care compounds (Myristic acid, 9-octadecenol, stearic acid, oleic Acid, arachidic acid, Erucic acid) in olive oil, groundnut oil, and palm kernel oil by using gas chromatography – mass spectroscopy. The %concentrations of the skin care compounds in the samples were: groundnut oil (4-phenylbut-3-ene-1-yne (5.79), Myristic Acid (8.63), Palmitic Acid (22.51), 9-octadecenol (12.76), Stearic Acid (10.89), Oleric Acid (8.34), Arachidic Acid (18.37), Erucic Acid (7.46); palm kernel oil (4-phenylbut-3-ene-1-yne (5.83), Myristic Acid (9.21), Palmitic Acid (32.04), 9-octadecenol (21.86), Stearic Acid (18.21), Oleric Acid (9.23), Arachidic Acid (11.24), Erucic Acid (0.96); olive oil (4-phenylbut-3-ene-1-yne (5.79), Myristic Acid (8.63), Palmitic Acid (22.51), 9-octadecenol (12.76), Stearic Acid (10.89), Oleric Acid (8.34), Arachidic Acid (18.37), Erucic Acid (7.46). The levels of skin care compounds follow this order: Palm kernel oil ? Groundnut oil = Olive oil, except arachidic acid and erucic acid. 1,2,3-trimethylbensene, p-mentha-1,3,8-triene, and o-cymene were not found in any of the oils. These ingredients delay ageing, eradicate pimples, rashes and other minute diseases and therefore enhance smoothness of the human skin. Therefore, palm kernel oil is the best oil to be applied on human skin as body cream than groundnut oil and olive oil, since it contains the highest % composition of the following skin care compounds; myristic acid, palmitic acid, 9-octadecenol, stearic acid and 2,3-epoxycarane.
The Fatty Acid Composition of Vegetable Oils and Their Potential Use in Wound Care
ADVANCES IN SKIN & WOUND CARE • JUNE 2019, 2019
OBJECTIVE: To evaluate the similarities among fatty acid compositions of vegetable oils sold in the Brazilian market and those present in a reference health product used to treat wounds. METHODS: The relative amounts of fatty acids in 21 types of vegetable oils, purchased in the Brazilian market, were assessed using gas chromatography-mass spectrometry and flame ionization detection. MAIN RESULTS: The studied oils had similar fatty acid compositions to the reference product (caprylic acid, 18.8%; capric acid, 17.4%; oleic acid, 27.5%; and linoleic acid, 28.1%). The presence of caprylic acid (10.45% ± 0.07%), capric acid (5.8% ± 0.75%), lauric acid (45.63% ± 0.93%), and myristic acid (16.33% ± 2.23%) were detected in all the vegetable oils tested. Oleic acid (52.94% ± 12.54%) was present in andiroba, avocado, canola, copaiba, olive, palm, pequi, and pracaxi oils and featured prominently in olive oil (75.8%). Linoleic acid (57.09% ± 8.47%) was present in corn, cottonseed, grapeseed, passion fruit, and sunflower oils and in mixed oils (olive with soybean and sunflower with corn and canola). CONCLUSIONS: Most of the vegetable oils tested are products of plants from tropical climates, where they are abundant and easy to cultivate. It is possible that a balanced composition of fatty acids obtained from natural sources could be an effective alternative treatment for wounds.
Omega–3 Fatty Acids PUFA - A Review PART I
Journal of Complementary Medicine
Alpha-linolenic acid (ALA) is the parent polyunsaturated fatty acid (PUFA) of the omega-3 family, which is essential to the human diet as many studies suggest that high amounts of omega-3 fats yields greater health benefit. Consumption of various foods providing PUFA could benefit in health areas such as metabolic syndrome and diabetes, inflammation and rheumatism, depression and mood disorders, and cancer and palliative care.