Systematic synthesis of specifically 13C 2H -labeled nucleosides from [ ul- 13C 6]- d-glucose (original) (raw)

A systematic approach, which combines previously reported reactions with appropriate modifications, was established for preparing a variety of selectively deuterated nucleosides from glucose• We have developed a systematic method of synthesizing specifically deuterated nucleosides from glucose. • 13 ?2 -13 2 Selectively C/H-doubly labeled nucleosldes, such as [1,2,3,4,5 -C5;3,5 -H2]-and [1,2,3,4,5 -13 , t I~ -. • ]3 J

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