" To Study the Clinico-Pathological Profile and Radiological Characteristics in Patients with Liver Abscess " (original) (raw)
Related papers
Clinical Pattern of Liver Abscess among the Patients Admitted in Rajshahi Medical College Hospital
Bangladesh Journal of Medicine, 2015
Introduction: Liver abscess is an important clinical problem in tropical regions of the world. Current assessment of liver abscesses should allow for better understanding of the aetiopathogenesis of the disease. This study was conducted to find the clinical pattern and aetiopathogenesis of liver abscess in patients admitted in Rajshahi Medical College Hospital. Methodology: The present cross-sectional study was carried out in the Department of Medicine, Rajshahi Medical College Hospital (RMCH) on consecutive 34 patients of liver abscess admitted between the period of July 2002 and June 2003. Detailed history and clinical examination were performed in all patients. All routine investigations were done. Liver abscess was confirmed by ultrasonography (USG). Aspiration of liver abscess was done under sonographic guidance in the Nuclear Medicine Department of RMCH to diagnose the cause of liver abscess. Aspirated materials were sent for microscopical examination and culture and sensitivity in the Department of Microbiology of the same Institute. Result: The findings showed that early middle-aged population were usually affected by liver abscess followed by middle aged (mean age around 40 years). The patients were predominantly male with males being 16 times more likely to suffer from the disease than the females. Most of the patients belong to low socioeconomic status (82.4%). All patients had fever and malaise. Other common manifestations were loss of appetite, lump in the abdomen, intercostal tenderness, nausea/ vomiting, loss of weight. Less common presentations were diarrhoea (29.4%), jaundice (23.5%), cough (11.8%), chest pain (11.8%) and breathlessness (2.9%). Liver span of the patients measured by ultra-sonogram showed hepatomegaly in all cases. All patients with pyogenic liver abscess and 75% of the patients with amoebic abscess had the history of prolonged intake of fermented palm juice (palm wine). Microscopic examination of the pus/aspirate drawn from the liver revealed trophozoite in 7(20.6%) cases. However, on culture of the specimen, 12(35.3%) were culture positive and 22(64.7%) were culture negative. Conclusion: Middle-aged male with low socioeconomic status with the history of prolonged palm wine intake are the most common characteristic of patients with liver abscess. Multi-center study with large sample size is recommended to verify the findings of the present study.
Internet Journal of Infectious Diseases
Evolution in diagnostics and treatment methodology has resulted in marked reduction in morbidity and mortality associated with liver abscess. Today with improved antibiotics and operative techniques, we could achieve much better response in patients with liver abscess. The presenting features, modes of treatment and clinical course were reviewed for 100 patients with liver abscess, seen in a single surgical unit at the SMS Hospital over one and a half year period. The aim of the study was to review the demographic data, aetiologies, investigations and to formulate the management plan of liver abscess patients.
Clinical, Laboratory, and Management Profile in Patients of Liver Abscess from Northern India
Objective. To describe the clinical profile, microbiological aetiologies, and management outcomes in patients with liver abscess. Methods. A cross-sectional study was conducted from May, 2011, to April, 2013, on 200 consecutive liver abscess patients at PGIMER and Dr. RML Hospital, New Delhi. History, examination, and laboratory investigations were recorded. Ultrasound guided aspiration was done and samples were investigated. Chi-square test and multivariate regression analysis were performed to test association. Results. The mean age of patients was 41.13 years. Majority of them were from lower socioeconomic class (67.5%) and alcoholic (72%). The abscesses were predominantly in right lobe (71%) and solitary (65%). Etiology of abscess was 69% amoebic, 18% pyogenic, 7.5% tubercular, 4% mixed, and 1.5% fungal. Percutaneous needle aspiration was done in 79%, pigtail drainage in 17%, and surgical intervention for rupture in 4% patients. Mortality was 2.5%, all reported in surgical group. Solitary abscesses were amoebic and tubercular whereas multiple abscesses were pyogenic (= 0.001). Right lobe was predominantly involved in amoebic and pyogenic abscesses while in tubercular abscesses left lobe involvement was predominant (= 0.001). Conclusions. The commonest presentation was young male, alcoholic of low socioeconomic class having right lobe solitary amoebic liver abscess. Appropriate use of minimally invasive drainage techniques reduces mortality.
A Cross Sectional Descriptive Study of Etiology and Clinical Pattern of Liver Abscess : 50 Cases
Chattagram Maa-O-Shishu Hospital Medical College Journal, 2013
Background: The liver is the organ most subjected to the development of abscesses and made up 48 % of all visceral abscesses' and 7% of all intra abdominal abscesses. Liver abscess should be suspected when there is a combination of fever, leucocytosis, constitutional symptoms, and pain in the right upper quadrant, and tenderness over the liver or right lower rib cage. The liver is affected by a number of local and disseminated infections; their frequency and types vary considerably around the world. Parasitic disorders are more prevalent in developing countries. Methods: It was a cross-sectional descriptive study. The cases were taken from the admitted patients of Medicine unit of SMCH, Chittagong. The study was conducted over a period of one year with a sample size of 50 patients and sample was taken by purposive sampling. Results: Among 50 patients 40 (80%) were diagnosed as ALA and 10 (20%) were diagnosed as PLA. ALA cases are common in 21-30 years age group & PLA cases are more common in >50 years of age group. Majority of the cases were from rural area. Common clinical features were fever, abdominal pain, nausea and tender hepatomegaly. Diarrhea was present on admission in 7 (15.9%) patients of ALA. Anaemia was common in both but polymorphonuclear leucocytosis was moderate to severe in PLA. Microscopic examination of stool samples for E. Histolytica trophozoites was positive in 3 (7.5%) cases and cysts in 4(10%) cases. Nine patients had right sided pleural effusion. Conclusions: Clinical features are common in both ALA and PLA. Liver abscesses are more common in men and more prevalent in rural areas. ALA more commonly occurs in 21-30 years age group but can occur at any age. Pyogenic abscess is more common in older age group (>50 years) and E. Coli is the commonest organism.
Clinico-Pathological Profile of Liver Abscess in a Teaching Hospital
TAJ: Journal of Teachers Association, 2009
The study was conducted to assess the clinico-pathological profile of 50 liver abscess cases. This study showed that liver abscess is more common in male than in female. In present study Amoebic Liver Abscess (ALA) is much more common than Pyogenic Liver Abscess (PLA) and almost all the cases belonged to low or medium socio-economic class from rural areas. This may be due to poor living conditions, over crowding and unhygienic practices which leads to fecal contamination of food and drinks which help in transmission of amoeba. Liver abscess has correlation with consumption of indigenous alcohol. Ultrasonogram is an easy, widely available non-invasive and dependable investigation to diagnose liver abscess. In the absence of sophisticated investigations (e.g. Serum antibody against amoeba) at hand, only aspiration and study of pus is a good guide to confirm and to differentiate ALA from PLA. Complications like recurrence, pleuro-peritoneal involvement or rupture of the abscess are not common. TAJ 2008; 21(1): 44-49
International Surgery Journal, 2018
Liver abscesses are infectious space-occupying lesions of liver. The two most common abscess being, pyogenic (PLA) of bacterial origin and amebic(ALA) of parasitic origin. While the mortality from liver abscess has decreased significantly since the early 20 century,the incidence appears to be increasing. Liver abscess has been described since the time of Hippocrates (4000 BC), who speculated that prognosis was related to the type of fluid recovered from the abscess. In 1938, Ochsner et al provided the first serious review of pyogenic abscesses in the pre-antibiotic era.
A STUDY ON LIVER ABSCESS IN A TERTIARY HOSPITAL
To study the demographic profile, clinical presentation and the etiological factors of liver abscess in adults clinical examination, biochemical culture from abscess drained & ultrasound findings. Patients with less than 20yrs and traumatic abscess, infected tumours are excluded from the study. The diagnosis of liver abscess was made by clinical features, radiological features and aspiration of pus with or without positive culture.
International Journal of Medical and Biomedical Studies
Introduction: A liver abscess is infective disease of liver parenchyma having collection of purulent material that can develop as a consequence of injury to the hepatic tissue or via portal vein from any source of infection within abdominal cavity. Mostly liver abscess are either due to amoebic infection or pyogenic bacterial infection but in some cases, etiologies like fungal, tubercular or sometimes mixed infections is also seen. Material and Methods: This present cross-sectional study was carried out by recruiting 137 patients diagnosed of having liver abscess at medical OPD at JLN Hospital, Ajmer during the year December 2019 – June 2021. All the patients with confirmed liver abscess were included in this study. Patients age below 18 years, critically ill patient (Including patients having ruptured liver abscess at the time of presentation and requiring surgical intervention), Pregnancy and GI Malignancy Results: 137 liver abscess patients were studied and males from lower middl...
Clinical and biochemical profile of liver abscess patients
International Journal of Research in Medical Sciences, 2017
Background: Liver comprises 48% of all the visceral abscesses. It is common in India with 2nd highest incidence due to poor sanitation, overcrowding and inadequate nutrition. Worldwide, approximately 40-50 million people are infected annually with amoebic abscesses. This study aims to observe the clinical and biochemical profile of liver abscess patients so that a prompt diagnosis can be made and early treatment can be given.Methods: The study was conducted over a period of 1 year on 50 patients of liver abscess. History and physical examination was done. All patients were subjected to complete hemogram, liver function test, coagulation profile (PT/INR) and USG abdomen. Serology for Entamoeba histolytica and HIV was done.Results: The mean age of the patients was 41.8 years with male preponderance. Amoebic liver abscess (86%) was predominant over pyogenic liver abscess (14%). Alcoholism (52%) and diabetes mellitus (20%) are main predisposing factors in case of liver abscess. Hepatome...