High Resolution Computed Tomography of the Lung in Patient with Interstitial Lung Diseases (original) (raw)

High Resolution Computed Tomography Scan Assessment of Different Interstitial Lung Diseases

Journal of Evidence Based Medicine and Healthcare, 2020

BACKGROUND Interstitial Lung Disease (ILD) is a group of diffuse lung parenchymal diseases characterized by the involvement of pulmonary interstitium. High resolution computed tomography (HRCT) is the cross-sectional imaging modality of choice for the diagnosis and follow up of ILD as it is accurate as well as non-invasive. The present study was done to describe the basic HRCT patterns associated with Interstitial Lung Disease and to correlate the HRCT patterns with clinical data to obtain differential diagnosis of Interstitial Lung Disease (ILD). METHODS 100 patients (41 males and 59 females) with a mean age of 50 years were included in this study during the period from July 2017 to June 2018. These patients were primarily diagnosed as having interstitial lung disease solely on the basis of clinical findings and chest x-ray by the Chest Medicine Department of BMCH and then referred to Radiology Department BMCH for HRCT assessment. RESULTS 74 patients were diagnosed to have interstitial lung disease and 26 patients had airway disease as well. The common frequent findings in interstitial lung disease (ILD) were idiopathic pulmonary fibrosis (UIP) (30%), idiopathic NSIP (21%), connective tissue disease related ILD (15%), extrinsic allergic alveolitis (EAA) (9%), pulmonary lymphangitis carcinomatosis (PLC) (6%) and 4% for each respiratory bronchiolitis associated interstitial lung disease (RB-ILD), bronchiolitis obliterans organizing pneumonia (BOOP), and occupational lung disease. Breathlessness on exertion (93.3%) and dry cough (100%) were the most common presenting symptoms of UIP. The HRCT findings of UIP included reticular shadowing (100%), nodular shadowing (16%), associated ground-glass attenuation in 73.3% and peribronchovascular thickening in 53%. The signs of lung fibrosis were honeycombing in 83.3%, traction bronchiectasis (66%), septal thickening (66%), core pulmonale in 30% and associated lung cancer in 10%. CONCLUSIONS UIP was the most common interstitial lung disease observed in our study. HRCT is the modality of choice in assessing diffuse parenchymal lung disease especially in the aspects of disease activity and earlier detection and characterization of disease.

Diagnostic Interstitial Lung Diseases in Patients Having Normal Chest Radiograph through High Resolution Computed Tomography

Journal of Health, Medicine and Nursing, 2021

Background: In Pakistan, the main cause of death is interstitial lung disease (ILD) i.e., 4.75%. In interstitial lung disease majority of the patients is about the age of 57.5 years. The age group maybe varying between the ages of 46 and 65 year. Female gender is more predominantly i.e., 65.6% in all types of ILD except the interstitial pulmonary fibrosis (P< 0.001). Objective: The aim of our study is to diagnose interstitial lung diseases in patients having normal chest radiograph through high resolution computed tomography. Study design: Our study design was cross-sectional descriptive study. Material and method: The descriptive cross-sectional study was conducted in which data of 100 patients were taken. The data was collected from the Radiology department of Sheikh Zayed Hospital Rahim Yar Khan. After informed consent, data was collected through CT Toshiba 164 slices. Result: 100 patients were included in our study out of which 61 were females and 39 were male's with the mean age of 49.32 years. The chest radiograph of the patients having ILD shows the patchy ground glass opacities (39.0%), consolidation of the lungs (21.0%), reticular shadowing (16.0%) and the pleural effusion (24.0%) while on the high-resolution computed tomography the patients were represented with ground glass haze (42.0%), calcific foci (21.0%), nodular lesion (16.0%), consolidation of the lungs (30.0%) and pleural effusion (22.0%).

High Resolution Computed Tomographic Evaluation Of Patients Suspected Of Having Diffuse Interstitial Lung Diseases With Radiographic Correlation

Background-Interstitial lung disease (ILD) consists of a diverse group of disorders that involve the pulmonary parenchyma, Interstitial lung disease may be caused a number of factors such as infections of the lungs; toxins in the environment, certain medications, radiation therapy to the chest, chronic autoimmune diseases: connective tissue diseases. Methods-Present cross sectional, institutional based study was conducted in Radiology department of RIMS, Ranchi between April 2009 to October 2010. A Pre tested semistructured questionnaire was used for interview of patients which were referred from various department. During study period 35 patients, between age group 20 to 70 years of age having History of dyspnea and chronic cough,History of exposure to organic/inorganic dust, Known case of collagenvascular disease(i.e. rheumatoid arthritis), Abnormal lung function test, Abnormal chest radiograph were interviewed and examined. Results-Out of 35 patients majority were male (82.9%), age group 41-50 years of age (34.2%),belong to low socio economic status (42.8%), having smoking habit (54.3%), moderate severity of dyspnoea(65.7%).Conclusion-HRCT is far superior to a radiograph in detecting changes within the interstitium when chest radiograph is normal.

HRCT Assessment of Interstitial Lung Diseases

Introduction: Interstitial lung disease (ILD) is a group of diffuse parenchymal lung diseases affecting the pulmonary interstitium. High resolution computed tomography) is the most accurate noninvasive, cross section imaging modality for the diagnosis and follow up monitoring of ILD. Study was done to check the basic HRCT patterns associated with Interstitial Lung Disease and correlation of HRCT patterns with clinical data in differential diagnosis of Interstitial Lung Disease. Material and methods: Total 50 patients referred from medicine department of our institute having clinical suspicion of ILD were studied during June 2015 to June 2016. HRCT chest was done in all patients on 6 slice Siemens somatom CT scanner in supine position using standard HRCT protocol. Parenchymal abnormalities were detected and categorized for specific diagnosis of ILD. Result: Majority of the patients (n=25) were between the ages of 60-80 years (8 males and 17 females). The major complaint was progressive dyspnea (n=48; 96%). The most common interstitial lung disease found in our study was usual interstitial pneumonia (n=18; 36%) followed by nonspecific interstitial pneumonia (n=7; 14%) and acute interstitial pneumonia (n=7; 14%). Conclusions: UIP was the most common interstitial lung disease observed in our study. Westernisation has changed the disease distribution in Indian population for age. In patients with progressive dyspnea ILD should be ruled out as a cause. Clinical and laboratory finding along with HRCT workup is essential for the diagnosis of specific ILD.

Role of High-resolution Computed Tomography Chest in Interstitial Lung Diseases

2016

Results: In this study, the age of the patients ranged from 22 to 85 years with mean age of 53.5 years, the majority of the patients were in age group 21-40 years (38%). There were 44% male patients and 56% female patients. The most common presenting clinical feature was dyspnea on exertion present in 64% of patients followed by a cough which was present in 60% of cases. Conclusion: In conclusion, high-resolution computed tomography is a valuable technique for evaluating the extent of lung involvement in various ILDs even when chest X-rays are normal.

Assessment of high resolution computed tomography in the diagnosis of interstitial lung disease

International Journal of Research in Medical Sciences, 2018

Background: Interstitial lung disease (ILD) are group of pulmonary disorders characterized by inflammation and fibrosis of gas exchanging portion of the lung and diffuse abnormalities on lung radiograph. Conventional computerized tomography plays a limited role in evaluation of interstitial lung disease due to its inability to demonstrate fine parenchymal details. High Resolution Computed Tomography (HRCT) is currently the most accurate non invasive modality for evaluating lung- parenchyma. So, the purpose of the study was to assess high resolution computed tomography in the diagnosis of interstitial lung disease.Methods: 50 patients with clinical suspicion of interstitial lung disease who were referred to Department of Radio-Diagnosis and Imaging for diagnosis and evaluation were subjected to both conventional radiography and HRCT.Results: Majority of the cases i.e. 9 (18%) had honeycombing, 8 (16%) cases had crazy paving pattern and mosaic attenuation, 7 (14%) cases had miliary mo...

Study of Interstitial Lung Disease With Reference to Radiological Profile

Asian Journal of Medical Radiological Research, 2018

Background: Interstitial lung disease Diagnosis requires extensive investigation into the patient's symptoms, life style, work history, exposures, and medications forming the clinical context. Subjects and Methods: The cross sectional perspective and high spatial resolution makes HRCT superior to other imaging modalities like chest X-Ray, lung tomography and conventional CT Scanning multiplanar imaging with aim to determine the radiological profile in a clinically suspected cases of Interstitial Lung Disease the present study conducted over 50 patients during the period of 12 months from October 2012 to October 2013 in kamineni hospital, Hyderabad. Results: Out of 50 clinically suspected patients of interstitial lung disease, a specific pattern was observed in 44patients on HRCT and 33 patients on chest radiograph. Patterns found on chest radiograph were correlated with patterns found on HRCT. Out of 44 interstitial lung diseases on HRCT, 28 patients revealed correlation between chest radiograph and HRCT pattern. Out of 50, thirty one patients had correlation between Chest radiograph and HRCT findings. Conclusion: HRCT is superior to chest radiograph in detection of all basic patterns associated with ILD and scores more in their distribution and lung parenchymal involvement.

Diagnostic Accuracy of Chest Radiograph in Interstitial Lung Disease as Confirmed by High-Resolution Computed Tomography (HRCT) Chest

Journal of Ayub Medical College Abbottabad

Background: Interstitial Lung Disease (ILD) - an umbrella term encompassing about 100 different pathophysiological entities are usually defined as an irreversible, progressive fibrotic changes in the lung parenchyma that leads to difficult breathing and reduced gaseous exchange at the alveolar level. We aimed to quantify the validity of CXR for the diagnosis of ILD taking HRCT as gold standard in the population of Hazara division. Methods: This validation study was conducted during 11 June till 12 Dec 2019 in the radiology department of Ayub Teaching Hospital, Abbottabad on 60 adult patients aged 30–60 years who presented with progressive exertional dyspnoea. The patients were enrolled into the study via non-probability, consecutive sampling technique. All the data was recorded on a self-developed structured questionnaire. Data was analyzed using SPSS version 20. Results: The mean age of study participants was 47.18±6.90 years SD with a range of 36–60years. The mean of time duration...